clinical-pharmacy-2017-posters-accepted-abstracts

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Journal of Pharmacology and Therapeutic Research
Volume 1 Issue 1 Clinical Pharmacy 2017
Notes:
Page 54
December 07-09, 2017 | Rome, Italy
7th World Congress on
Clinical Pharmacy and Pharmacy Practice
Multiprofessional medical review among
frail elderly people living in nursing homes:
What is the impact on appropriateness and
outcomes?
Chiara Cattaruzzi, Laura Cadelli, Lucrezia Marcuzzo, Antonella
Antonini, Barbara Groppo and Barbara Ros
Integrated University Healthcare Company of Udine, Italy
Background: Polypharmacy and inappropriate
prescribing is common in elderly patients and is associated
with medication errors, adverse drug reactions and
length of hospital stay. Interventions aimed to optimize
prescribing appropriateness have been successfully
applied in hospital settings. However, there is a paucity of
data about the effect of a multiprofessional approach on
clinical outcomes in people living in nursing homes.
Objectives: The aim of this study was: to evaluate
prescribing appropriateness of therapies in elderly patients
residing in nursing homes; to evaluate the impact of this
intervention on healthcare outcomes such as admission to
Emergency Department (ED) and hospitalization; and to
investigate critical areas where further intervention would
be required
Methods: We conducted a prospective observational
study in 351 frail subjects aged >65 years, who lived in
7 nursing homes between April 2014 and September
2016. Clinical pharmacists reviewed each drug regimen
and suggested written modifications on drug use to
physicians and nurses. Criteria for optimizing therapies
were the START-STOP Criteria, the adherence to the
drug formulary or to product information. Drug-drug
interactions were also evaluated. Patient medical records
were accessed through the regional electronic healthcare
database to collect clinical outcomes at six-month.
Preliminary Results: A significant decrease in the
prevalence of inappropriate prescriptions (43.9% to
20.9%, p<0.001), drug interactions (13.1 to 7.8%, p<0.001)
and in the total number of drugs (3009 to 2757, p=0.008)
was observed. Drug withdrawal rate was 17% of total
prescriptions. No statistical reduction in hospitalization or
ED admission was shown.
Conclusions: A multiprofessional approach to medical
review process was successful for decreasing drug
inappropriateness, drug interactions and total number
of prescribed medications. At least three critical areas
in which intervention and training was required were
identified: polypharmacy, inadequate severe interactions
risk perception and crush drug administration.
J Pharmacol Ther Res 2017