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Journal of Nutrition and Human Health | Volume 3
J Nutr Hum Health, Volume 3
November 21-22, 2019 | Singapore
Clinical Nutrition and Fitness
17
th
International Conference on
Association between Onodera’s prognostic nutrition index and infection-related
hospitalizations in patients with schizophrenia
Bo-Jian Wu
Yuli Hospital, Taiwan
Background:
Protein-energy wasting is associated with poor
outcome in various clinical settings. However, the prevalence of
moderatemalnutritionand theprognostic impact of nutritional
status are rarely explored in hospitalized patients with
schizophrenia. This study aimed to assess the prevalence of
moderate malnutrition and the predictive ability of Onodera’s
prognostic nutrition index (OPNI) on occurrence of infection-
related hospitalizations for hospitalized schizophrenia patients.
Methods:
All measurements, including nutritional assessment
were performed among hospitalized 582 patients with chronic
schizophrenia (64.8% man, mean age 53.8 ± 9.6 years). The
mean follows up period was 408 days. Cox regression models
adjusting for age, sex and Charlson comorbidity index, were
used to explore the association between OPNI and infection-
related hospitalizations.
Results:
At the end of the study, 42 patients had infection-
related hospitalizations. The prevalence of moderate
malnutrition defined by OPNI scores lower than 45was 15.8%
(92/582). Moderate malnutrition expressed a significant
association with falls in this study. The adjusted hazard
ratios (95% confidence intervals) of moderate malnutrition
were 2.42 (1.17–4.59) for infection-related hospitalizations.
Conclusions:
OPNI is a useful tool for identifying chronic
schizophrenic patients at risk of moderate malnutrition
and infection-related hospitalizations. Further studies are
needed to explore whether early detection of patients
with schizophrenia at risk for malnutrition could reduce
the morbidity and mortality by appropriate interventions
Speaker Biography
Bo-Jian Wu has completed his MD from National Défense Medical Center
in Taiwan. He has completed his MSc from the Institute of Epidemiology of
National Taiwan University and Ph.D. from the institute of Clinical Medicine
of National Yangming University. Now he is certified psychiatrist, and an
attending physician of Department of Psychiatry, Yuli Hospital, Ministry
of Health and Welfare, Hualien, Taiwan. His research mainly focus on
schizophrenia, and have over 30 publications.
e:
woobojian@gmail.com