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S e p t e m b e r 1 0 - 1 1 , 2 0 1 8 | D u b l i n , I r e l a n d
Cell and Gene Therapy 2018 & Clinical Microbiology Congress 2018
Note:
Page 17
allied
academies
CLINICAL AND MEDICAL MICROBIOLOGY
CELL AND GENE THERAPY
&
World Congress on
International Conference on
Joint Event on
Biomedical Research
|
ISSN: 0976-1683
|
Volume 29
Chonghe Jiang, Biomed Res 2018, Volume 29 | DOI: 10.4066/biomedicalresearch-C3-006
EARLY AND RAPID PREDICTION
FOR POSTOPERATIVE INFECTIONS
FOLLOWING PERCUTANEOUS
NEPHROLITHOTOMY IN PATIENTS WITH
COMPLEX KIDNEY
Purpose:
The purpose of the study is to obtain more accurate and rapid
predictors for systemic inflammatory response syndrome (SIRS) after
percutaneous nephrolithotomy (PCNL) in complex kidney stone patients and
provide evidence for early prevention and treatment of postoperative infections.
Methods:
A total of 802 complex kidney stone patients undergone PCNL from
September 2016 to September 2017 were recruited in the study. Urine tests,
urine cultures and stone cultures were performed, the perioperative data were
prospectively recorded.
Results:
62 (7.7%) patients developed postoperative SIRS. A multivariate
logistic regression analysis revealed that operating time ≥100 min, urine tests
with both positive urine leukocyte and positive urine nitrite (UL+UN+), positive
urine cultures (UC+) and positive stone cultures (SC+) were independent risk
factors of SIRS. The incidence of postoperative SIRS was higher in UL+UN+
(28.7%) and both UC and SC were positive (UC+SC+; 28.8%) patients than that
in any other patients (p<0.05). Preoperative UL+UN+ can be used to predict
UC+SC+ with accuracy of more than 90%. The main pathogens in kidney stones
were
Escherichia coli
(43.8%),
Proteus mirabilis
(14.0%),
Staphylococcus
(7.4%),
while main pathogens in urine were
Escherichia coli
(53.8%),
Enterococcus
(9.4%) and
Proteus mirabilis
(7.6%). The occurrence of
Escherichia coli
was
more frequent in group with SIRS than in group without SIRS (p<0.05).
Conclusions:
UL+UN+ in preoperative urine tests could be considered as the
early and rapid predictor for UC+SC+ and postoperative SIRS. SIRS following
PCNL was more related to
Escherichia coli
infections in complex kidney stone
patients.
Biography
Chonghe Jiang is the first Research Engineer of
Linkoping University, Sweden. Currently, he is work-
ing in Qingyuan People’s Hospital of Guangzhou
Medical University, China as a Professor, Urologist
and Director of Kidney Center. He is a major in re-
search work on voiding dysfunctions, and clinical
work on urinary tract stone and infections. All his
publications are involved in neuron control of lower
urinary tract and identifying and clarifying the blad-
der cooling reflex and applying neuro-modulatory
technique in treatment of urinary incontinence by
using electrical stimulation are main contributions
in this area.
jch13927625023@qq.comChonghe Jiang
Qingyuan People’s Hospital, China