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February 25-26, 2019 | Paris, France
13th World Cancer Congress
Journal of Medical Oncology and Therapeutics | Volume 4
Thoracic manifestations of Breast Cancer are most commonly related to metastases and can be
observed in long time after the diagnosis of Breast Cancer
Ayda Hussain Omer Mustafa
University of AL-Neelain, Sudan
The objective of the study is to evaluate the thoracic
manifestations in Sudanese patients with breast cancer. This
is a prospective descriptive cross-section hospital-based study,
carried out during the period from January to September 2017
at private clinic of breast cancer of Dr. Ayda Hussein, Respiratory
Department in Alshaab Teaching Hospital and Oncology Units at
Alamel Tower, included all patientswith breast cancer associated
with thoracic abnormalities, which confirmed clinically and
radiologically by chest X-ray and CT chest. The datawas collected
by questionnaire then analyzed by computer using SPSS.
A total of 70 patients with breast cancer were evaluated
clinically and radiologic ally, 68 (97.1%) were females and 2
(2.9%) were males, the mean age was (49.91 ± 18.26) years, 39
(55.07%) were from Khartoum and 31 (44.93%) patients from
outside Khartoum State, 47 (67.1%) patients not smokers, the
time interval between the diagnosis of primary breast cancer
and detection of thoracic manifestations was found to be 1-3
years in half of the study population 35 (50.0%), and <1 year
in 16 (22.9%) patients, while 4-6 years in 19 (27.1%) patients,
59 (84.3%) patients were with unilateral breast cancer, while,
11 (15.7%) patients were with bilateral breast cancer. The
symptoms of thoracic manifestations, were SOB in 68(97.1%)
cases, cough in 59 (84.3%) patients [38 (64.4%) productive
cough and 21 (35.6%) dry cough], 29 (41.4%) patients had chest
pain, fever, weight loss, and hemoptysis were 25 (36.2%), 24
(34.3%), and 11(15.7%) respectively. Thoracic manifestations
of the breast cancer radio logically based on X-ray were pleural
effusion in 39 (55.7%) patients, nodules in 26 (37.1%) patients,
consolidation in 13 (18.6%) patients, Infiltration (lymphangities
carcinomatosis) in 7 (10.0%) patients, Cavity in 6 (8.6%) patients
and mass in 6 (8.6%), Reticulation in 1(1.4%) patients, while
detection radiologically based on CT were pleural effusion was
found in 39 (55.7%) patients, nodules in 26 (37.1%) patients,
consolidation in 13 (18.6%) patients, pulmonary embolism in
7 (10.0%) patients, lymphangities carcinomatosis in 6 (8.6%)
patients, mass in 5 (7.1%), Cavity in 4 (5.7%) patients and fibrosis
in 3 (4.3%). Among patients with Pleural effusion, 19 (48.7%)
developed right sidedpleural effusion, 15 (38.5%) developed left
sided pleural effusion, and 5 (12.8%) developed bilateral sided
pleural effusion. There was statistically insignificant correlation
between presences of nodule, pleural effusion and the side of
breast cancer (P. value = 0.735, P. value = 0.735) respectively.
e:
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