cancer-nursing-2019-keynote

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allied
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April 15-16, 2019 | Frankfurt, Germany
Oncology Nursing and Cancer Care
16th International Conference on
Page 12
Notes:
Journal of Medical Oncology and Therapeutics | Volume 4
Canceristheleadingcauseofdeathworldwide.The
human cytomegalovirus (HCMV) plays important
role in several malignancies including breast cancer,
colorectal cancer, brain tumor and others. Breast
cancer is considered as the leading cause of deaths
among women. Previous reports have demonstrated
that the HCMV genome contains oncogenic genes
and have potential to cause the different types
of cancer. The HCMV is a betaherpes virus and its
primary infection leads to the lifelong latent or
persistent infection. The primary HCMV infection
is asymptomatic and may cause the severe health
issues in immunocompromised population especially
in organ transplant patients, AIDS or cancer patients.
Furthermore, the congenital HCMV infection causes
the fetus malformation and is the leading cause of
birth defects. Studies have found HCMV DNA in the
numerous forms of tumors and concurrent HCMV
specific antibodies in cancer patients. Taken together,
these findings suggested a connection between
HCMV and cancer progression. In this study, we
aimed to identify and study themain factors encoded
by HCMV which are responsible for the breast and
brain cancer development. We are using a robust,
tightly controlled, reversible and highly sensitive AID
system to study the HCMV encoded proteins and
their roles in cancer development
Speaker Biography
Dabbu Kumar Jaijyan is currently a scientist at New Jersey Medical
School, Rutgers University, USA. He completed his PhD in Biotechnology
at National Institute of Immunology, India and completed his MSc at
Jawaharlal Nehru University, India. He also did his under graduate in the
year 2003-2006 at Delhi University, India. He has over 5 publications and
has been working on the infectious disease caused by the viruses like VZV,
HIV, CMV and ZIKA. He has developed a model to study the role of HCMV
induced tumor and also been involved in developing therapeutic tools in
collaboration with world renowned pharmaceutical industries.
e:
Dabbu Kumar Jaijyan
Rutgers University, USA
Unraveling the role of HCMV in Glioblastoma progression using an
inducing HCMV model