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May 20-21, 2019 | Vienna, Austria

Biomaterials and Nanomaterials &

Materials Physics and Materials Science

International Conference on

Journal of Materials Science and Nanotechnology | Volume 3

Biotolerability of intracortical microelectrodes

Eduardo Fernandez

University Miguel Hernández, Spain

here are different ways to profitably apply smart,

i.e. stimuli responsive, polymers to the field of

biomaterials. Shape memory polymers (SMPs) have a high

potential for applications in minimally invasive surgical

procedures allowing the design of devices that can modify

their macroscopic properties when receiving a stimulus by

the human body. Shape Memory Polyurethanes (SMPU)

were investigated as promising candidate materials for the

repair of bone defects and cerebral aneurism occlusion.

Porous SMPU structures were fabricated by foaming

processes and their potential biomedical application was

evaluated. Thermo responsive polymers undergoing a

“reverse” sol-gel transition can be used in Regenerative

Medicine to develop smart cell culture surfaces fromwhich

to obtain intact cell sheets (Cell-Sheet Engineering, CSE).

Recently, extrusion-based bioprinting of methylcellulose

(MC)-based hydrogels was used to produce MC hydrogel

rings onto which cells sheets were successfully obtained

with murine embryonic fibroblasts and endothelial murine

cells.