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allied
academies
Joint Event
February 21-22, 2019 | Paris, France
Microbiology & Applied
Microbiology
2nd International Conference on World Congress on
Wound Care, Tissue Repair
and Regenerative Medicine
&
Journal of Trauma and Critical Care | Volume 3
Human papillomavirus infection in genital women in four regions of Senegal
El Hadji Seydou Mbaye1,2, Tarik Gheit1, Ahmadou Dem2, Sandrine McKay-Chopin1, Ndeye Coumba Toure-Kane2, Souleymane Mboup 2,
Massimo Tommasino1, Bakary S Sylla1 and Cheikh Saad Bouh Boye 2
1 International Agency for Research on Cancer (IARC/WHO), France
2 Aristide Le Dantec Hospital, Senegal
Cervical cancer is the most frequent cancer among women in
Senegal. However, there are few data concerning the HPV types
inducing neoplasia and cervical cancers and their prevalence, in
the general population of Senegal.
Aim: The aim of this study is to determine the prevalence of
HPV infection in Senegalese women aged from 18 years and
older.
Materials and Methods: A study was performed on 498
cervix samples collected from healthy women aged 18 and
older in Dakar. 438 other samples were collected from three
other regions, Thies, Saint Louis and Louga. The samples were
screened for 21 HPV genotypes using an HPV type-specific E7
PCR bead-based multiplex genotyping assay (TS-MPG) which is
a laboratory-developed method for the detection of HPV.
Results: The prevalence for pHR/HR-HPV in the region of Dakar
was 20.68%. HPV 52 (3.21%) was the most prevalent HPV type,
followed by HPV 16 (3.01%) and HPV 31 (3.01%). In the regions
of Thies, Louga and Saint Louis, the prevalence for pHR/HR-HPV
was 29.19%, 23.15% and 20% respectively.
Conclusion: The study revealed the specificity of the HR-HPV
prevalence in Dakar and other regions of Senegal. The patterns
differs from the one observed in the other regions of the world
and rise the issue of the development of vaccination program in
the country. Such a program should take into account the real
HPV prevalence for an effective protection of HPV-associated
diseases.
Speaker Biography
El Hadji Seydou Mbaye was born in 1978 in Kaolack a region of Senegal. During 2008-
2013, he pursued his PhD in Biology and Human Pathologies with the collaboration
of the International Agency for Research on Cancer (IARC) /WHO, Lyon (France); he
was certified by the Federation International of Gynecology Obstetrics (FIGO), the
Accreditation Council of Oncology in Europe (ACOE, ), the Institute
Catalan of Oncology (ICO) for cervical cancer prevention in support of CME for
physicians. These credits are also recognised as Physician’s Recognition Award (AMA
PRA Category 1 credits) by the American Medical Association. He was certified by the
United Nations for Basic Notion of Security on the Ground-Protection, Health and
behavior, by the International Agency for Research on Cancer (IARC)/World Health
Organization, Lyon (France) for Safety Certificate. He has published 1 Book with a style
of philosophical story. Author of the world program against cancer in low and middle
incomes countries, he is first authoring of more than 90 articles published in reputed
journals. He is editorial board member of the International Journal of Immunology,
associate membership of the World Society for Virology and also, member of BCNet
International Working Group, International Agency for Research on Cancer (IARC)/
World Health Organization (WHO).
e:
El Hadji Seydou Mbaye et al., J Trauma Crit Care, Volume 3
DOI: 10.4066/2591-7358-C1-002