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Dermatol Res Skin Care 2017 | Volume 1 Issue 1
World
Dermatologist Summit and Skin Care Expo
October 30-31, 2017 | Toronto, Canada
Background:
Uveitis has been associated with psoriatic
arthritis, but the relationship between uveitis and psoriasis
is unsettled.
Objective:
To evaluate the risk of uveitis in people with
psoriasis and psoriatic arthritis. Methods: We conducted a
cohort study to assess the risk of incident uveitis in people
affected by mild and severe psoriasis with and without
psoriatic arthritis.
Results:
We identified 8,602 people with psoriasis (including
531 with psoriatic arthritis and 8,071 without psoriatic
arthritis) and 917,596 nonpsoriatic controls. Only the severe
psoriasis with psoriasis arthritis group had a higher risk of
incident uveitis (adjusted incidence rate ratio (IRR) 3.31, 95%
CI 1.07-10.25) than nonpsoriatic controls. The association
became stronger in the sensitivity analysis limiting to
incident anterior uveitis (adjusted IRR 4.00, 95% CI 1.29-
12.41). The mild psoriasis with psoriatic arthritis group and
the mild/severe psoriasis without psoriatic arthritis groups
did not have an increased risk of incident uveitis.
Conclusions:
Only people with severe psoriasis and psoriatic
arthritis have an increased risk of incident uveitis, while
those with mild psoriasis and psoriatic arthritis and those
with psoriasis but no psoriatic arthritis do not.
e:
ch2876@chgh.org.twRisk of uveitis in people with psoriasis and psoriatic arthritis: A 10-year nationwide cohort study
Tao-Hsin Tung
Department of Medical Research and Education, Taiwan