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J Parasit Dis Diagn Ther 2017

Volume 2 Issue 3

September 7-8, 2017 | Edinburgh, Scotland

4

th

International Conference on

Tropical Medicine, Infectious Diseases & Public Health

Notes:

Tropical Medicine 2017

Shigeyuki Kano, J Parasit Dis Diagn Ther 2017

THE DETECTION OF HIDDEN

PLASMODIUM INFECTION IN LAOS

M

icroscopy and malaria rapid diagnostic tests (RDTs)

are used to diagnose malaria in the Lao PDR. In

order to evaluate the performance of a highly sensitive PCR

technique in comparison to microscopy and the RDTs, as well

as to understand the precise malaria situation, a small pilot

study was conducted in a highly endemic Attapeu province

in 2015. 381 volunteers from villages in Attapeu participated

in the survey. Microscopy, RDTs and a real-time nested PCR

were used to detect Plasmodium infections and their results

were compared. The numbers of infections detected by the

3 methods were as follows: 1 P. falciparum and 2 P. vivax by

microscopy; 2 P. falciparum and 3 P. vivax by RDTs; and 35

Plasmodium including 2 P. falciparum, 32 P. vivax and 1 mixed

infection by the PCR. All the participants with parasitemia

were asymptomatic showing body temperatures of <37.1°C.

It was reported in the “World Malaria Report 2016” that the

malaria burden in the Lao PDR was, as a whole, decreasing,

but our present study provide that many asymptomatic

Plasmodium carriers were in the study area, of whom P. vivax

was the dominant species as high as 94.3%. In fact, Ministry

of Health of Lao PDR has declared that malaria is to be

eliminated by 2030 in the country. To achieve this goal, highly

sensitive diagnostic tests including PCR-based diagnostic

methods should be employed, and targeted elimination plans

for the hidden P. vivax infections should be designed and

implemented.

Biography

Shigeyuki Kano is director of the department of tropical medicine and malaria, research

institute, national center for global health and medicine, japan. He is President of

Japanese Society of Tropical Medicine, and presently, Board Member of the Japanese

Society of Parasitology, member of ASTMH, Fellow of RSTMH. He is serving as an

advisor to Japan International CooperationAgency (JICA) for the malaria control project

under Japanese ODAand as a TRPmember of Global Fund. He also belongs to Institut

Pasteur du Laos as Head of Lao-Japan Parasitology Laboratory under SATREPS

(JICA/AMED) Project.

kano@ri.ncgm.go.jp

Shigeyuki Kano

Narional Centre of Global Health and Medicine, Japan