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J Parasit Dis Diagn Ther 2017
Volume 2 Issue 3
September 7-8, 2017 | Edinburgh, Scotland
4
th
International Conference on
Tropical Medicine, Infectious Diseases & Public Health
Notes:
Tropical Medicine 2017
Shigeyuki Kano, J Parasit Dis Diagn Ther 2017
THE DETECTION OF HIDDEN
PLASMODIUM INFECTION IN LAOS
M
icroscopy and malaria rapid diagnostic tests (RDTs)
are used to diagnose malaria in the Lao PDR. In
order to evaluate the performance of a highly sensitive PCR
technique in comparison to microscopy and the RDTs, as well
as to understand the precise malaria situation, a small pilot
study was conducted in a highly endemic Attapeu province
in 2015. 381 volunteers from villages in Attapeu participated
in the survey. Microscopy, RDTs and a real-time nested PCR
were used to detect Plasmodium infections and their results
were compared. The numbers of infections detected by the
3 methods were as follows: 1 P. falciparum and 2 P. vivax by
microscopy; 2 P. falciparum and 3 P. vivax by RDTs; and 35
Plasmodium including 2 P. falciparum, 32 P. vivax and 1 mixed
infection by the PCR. All the participants with parasitemia
were asymptomatic showing body temperatures of <37.1°C.
It was reported in the “World Malaria Report 2016” that the
malaria burden in the Lao PDR was, as a whole, decreasing,
but our present study provide that many asymptomatic
Plasmodium carriers were in the study area, of whom P. vivax
was the dominant species as high as 94.3%. In fact, Ministry
of Health of Lao PDR has declared that malaria is to be
eliminated by 2030 in the country. To achieve this goal, highly
sensitive diagnostic tests including PCR-based diagnostic
methods should be employed, and targeted elimination plans
for the hidden P. vivax infections should be designed and
implemented.
Biography
Shigeyuki Kano is director of the department of tropical medicine and malaria, research
institute, national center for global health and medicine, japan. He is President of
Japanese Society of Tropical Medicine, and presently, Board Member of the Japanese
Society of Parasitology, member of ASTMH, Fellow of RSTMH. He is serving as an
advisor to Japan International CooperationAgency (JICA) for the malaria control project
under Japanese ODAand as a TRPmember of Global Fund. He also belongs to Institut
Pasteur du Laos as Head of Lao-Japan Parasitology Laboratory under SATREPS
(JICA/AMED) Project.
kano@ri.ncgm.go.jpShigeyuki Kano
Narional Centre of Global Health and Medicine, Japan