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Journal of Clinical and Experimental Toxicology | Volume: 2

December 03-04, 2018 | Dubai, UAE

International Conference on

6

th

International Conference on

Toxicology, Clinical Toxicology & Pharmacology

Recycling & Waste Management

Joint Event

&

E

ndocrine disrupting chemicals (EDCs) are of global concern

and find their way to the marine environment via the

sewage treatment plants (STPs). Dumping untreated sewage to

the coastal areas is one of the critical stressors to Kuwait marine

environment, which can deteriorate the quality of seawater and

sediment. This study was designed to investigate the status and

sources of EDCs and their effect on fish in Kuwait’s coastal areas.

The analysis of field samples from exposure sites revealed

significant levels of EDCs in seawater (phthalates: 2.1 to 4.6 µg/l;

alkylphenols: 1.2 to 16.4 ng/l; estrogens: 0 to 36.2 ng/l) which

clearly indicated a local source or chronic input of untreated or

partially treated water. Sediment samples showed significant

levels of the three main classes of EDCs (phthalates: 2.1 to 15.7

mg/kg drywt; alkylphenols: 2.5 to15.1µg/kg drywt.; estrogens:

4.1 to 214.2 µg/kg dry wt.) which indicated a possible release

from sediment which acts as a reservoir for pollutants. Yellow-

finned seabream (

Acanthopagrus latus

) were placed in cages

and exposed near sewage discharge areas for two weeks. Fish

liver were dissected for histology and immunohistochemistry

and the results revealed hepatic alteration in fish liver samples

in the form of hepatic depositions and necrotic changes

although no marked deviation in the structural integrity of the

hepatic tissue was observed. Vitellogenin (Vtg) localization was

also detected in liver samples correlated with the EDCs levels

in seawater and sediment samples. The existing levels detected

in Kuwait marine environment posed a physiological effect on

fish and Kuwait Bay is very important and sensitive ecological

system which should be protected from all kinds of stressors

especially the anthropogenic.

Speaker Biography

Noura Al-Jandal has completed her PhD on 2011 from the University of Exeter,

UK. She is an Associate Research Scientist in the Environmental and Life Sciences

Research Center at the Kuwait Institute for Scientific Research working on endocrine

disrupting chemicals effect on marine biota. She lead several client funded project

and published he work in peer-reviewed journals. She is a member in the Associate of

the Higher Education Academy (AHEA) and a qualified British Sub-Aqua Club (BSAC)

Diving License Holder. She presented her work in several international conferences

as a speaker. Recently she gave an Oral presentation in Conference Series the 12th

International Conference on Environmental Toxicology and Ecological Risk Assessment

held during in Atlanta, Georgia, USA. Currently she is working on projects of a high

global significance such as microplastics assessment in Kuwait marine environment.

e:

njandal@kisr.edu.kw

Noura Al-Jandal

Kuwait Institute for Scientific Research, Kuwait

Assessment of endocrine disrupting chemicals in Kuwait coastal area and its impact

on marine fish

Noura Al-Jandal

, Toxicology 2018, Recycling 2018, Volume 2

DOI: 10.4066/2630-4570-C1-001