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Page 79
allied
academies
International Surgery and Ortho Conference
October 25-26, 2017 | Toronto, Canada
Case Rep Surg Invasive Proced 2017 | Volume 1 Issue 3
M
orbidity and mortality are mainly rooted in valvular
heart disease which is also associated with the result
of congenital malformations. In fact, it is important to pay
a precise attention to the fact that by the amalgamation
of human being increased understanding of heart valve
development and major advances in genetic technologies,
and by considering the success of the Human Genome
Project, heart valve diseases rooted in numerous genetic
contributions have been discovered. The present paper will
summarize the review of the related literature regarding the
two-common familial VHDs which have the genetic basis,
namely such as mitral valve prolapses and bicuspid aortic
valve; it also highlights some of the recent findings that
boosts our understanding of pathogenesis in such diseases.
The main objective of the present paper is to meet the needs
of clinicians by providing a good command of knowledge on
elaborating the notion of genetic contributions as one of the
main sources in valvular heart diseases.
e:
r0jiar.asgarian@gmail.comGenetic basis of heart valve diseases; bicuspid aortic valve and mitral valve prolapse
Rojiar Asgarian, Maryam Eslami
and
Fateme Chegini
Islamic Azad University, Iran