2 / 13
Page 43
N o v e m b e r 1 2 - 1 3 , 2 0 1 8 | R o m e , I t a l y
Joint Event on
OF EXCELLENCE
IN INTERNATIONAL
MEETINGS
alliedacademies.comYEARS
Surgery and Anesthesia 2018 & Euro Gastro Congress 2018
Case Reports in Surgery and Invasive Procedures
|
Volume 2
&
GASTROENTEROLOGY
3
rd
International Conference on
SURGERY AND ANESTHESIA
International Conference on
Sang Min Lee, Case Rep Surg Invasive Proced 2018, Volume 2
LOWER RISK OF GASTRIC ATROPHY
AND INTESTINAL METAPLASIA IN MALT
LYMPHOMA PATIENT DESPITE OF
H.
PYLORI
INFECTION
Sang Min Lee
The Catholic University College of Medicine, South Korea
Background/Aims:
Atrophic gastritis and intestinal metaplasia are sequential
consequences of chronic
H. pylori
infection.
H. pylori
infection is well known
risk factor for gastric adenocarcinoma and malt lymphoma of stomach. Atro-
phic gastritis and intestinal metaplasia increases the risk of gastric adeno-
carcinoma development. The relationship between gastric malt lymphoma
and atrophic gastritis-intestinal metaplasia is not on the spot of interest. We
here investigated the clinical characteristics of gastric MALT lymphoma and
co-presence of atrophic gastritis and intestinal metaplasia.
Materials and methods:
Study was conducted by review of electronic medi-
cal record of patients who were diagnosed with gastric malt lymphoma at an
academic institute, the Yeouido St. Mary’s hospital, Seoul, Korea, from Janu-
ary 2001 to Mar 2018. Clinical characteristics and pathologic backgrounds
including
H. pylori
infection positivity, atrophic gastritis and intestinal meta-
plasia were investigated.
Results:
A total of 47 subjects were enrolled consecutively during the study
period and analyzed retrospectively. The mean age was 57.19-year-old (range
36 ~ 85). The male to female ratio was 1.19 (25/21). Endoscopic appearanc-
es varied; thirteen subjects presented ulcerative mass (28.26%), 12 (26.09%)
flat atrophic patch of discoloration, 16 (34.78%) erosive patches, 2 (4.35%)
multiple polypoid lesions and 3 (6.52%) sub epithelial tumor like appearance.
H. pylori
infection was proved in 82.6% (38 / 46). On histologic examination,
background atrophic gastritis-intestinal metaplasia was accompanied in
28.26% (13/46). Serum pepsinogen I and II, as serological marker for atrophy,
was evaluated in 17 subjects. Only 5 of 17 (29.41%) showed compatible with
atrophic gastritis (pepsinogen I / II ratio of less than 3).
Conclusion:
The background mucosa of gastric malt lymphoma differs from
that of gastric adenocarcinoma in terms of atrophic gastritisintestinal meta-
plasia. Less than 30% of gastric malt lymphoma accompanied background
atrophic gastritis. Age can be a confounding factor. We will precede the age
matched comparison between patients with gastric adenocarcinoma and
malt lymphoma.
Sang Min Lee is a graduate of Kyungpook national uni-
versity medical school in Korea and has completed ma-
jor training at the department of internal medicine, the
Catholic university of Korea. Currently, he is in training
for fellowship at the department of internal medicine of
Yeouido St. Mary’s hospital Sang Min Lee is majoring in
gastroenterology and is working to become the best gas-
troenterologist & endoscopic specialist in South Korea.
sss-bluesky@hanmail.netBIOGRAPHY