4 / 7
Page 26
allied
academies
WORLD CONGRESS ON SMART MATERIALS AND STRUCTURES
&
3
rd
International Conference on
POLYMER CHEMISTRY AND MATERIALS ENGINEERING
November 21-22, 2019 | Singapore
Joint event on
Materials Science and Nanotechnology | Volume: 03
Notes:
Development of polyhydroxyalkanoate-based biomaterials for bone tissue regeneration
Maciej Guzik
1
, Katarzyna Haraźna
1
, Tomasz Witko
1
, Ewelina Cichoń
2
, Szymon Skibiński
2
, Aneta Zima
2
, Anna
Ślósarczyk
2
, Ipsita Roy
3
1
Jerzy Haber Institute of Catalysis and Surface Chemistry Polish Academy of Sciences, Poland
2
Faculty of Material Science and Ceramics, AGH University of Science and Technology, Poland
3
Departament of Materials Science & Engineering, Kroto Research Institute, University of Sheffield, United Kingdom
B
io polymers represent one of the leading sectors
for bio-based products and their expected growth
is foreseen to be significant within the next years.
Polyhydroxyalkanoates (PHAs), a class of optically active
biodegradable polyesters, are accumulated by numerous
bacteria, they are non-toxic and degrade to harmless
products. PHAs are excellent bio compatible materials due
to the lack of toxicity in contact with human tissue and
blood. Development of new composite materials for bone
tissue engineering is a constantly growing field of medicine.
Therefore there is a continuous need in creating novel
materials that can not only regenerate the defected tissue
but also nourish it while the healing process progresses.
Here we present a concept of 3D ceramic-polymer scaffolds
prepared from one of the representatives of medium chain
length polyhydroxyalkanoates, with possibility to use them
in regeneration of hard tissue. Two different materials
for bone tissue regeneration were prepared: a series of
macroporous ceramic composites coated with modified
as well as unmodified PHA polymer. We present their
morphology along with physicochemical and biological
characteristics.
Research funded by The National Centre for
Research and Development, grant TechMatStrateg no.
TECHMATSTRATEG2/407507/1/NCBR/2019.
Biography
Maciej Guzik graduated from Jagiellonian University in Kraków,
Poland with MSc in environmental protection in 2008. Next, he'd
undertaken a structured PhD programme at University College
Dublin in Ireland. During that time he had been specialised in high
cell density fermentation development, downstream and upstream
processing of polyhydroxyalkanoates (PHAs), and also genetic
manipulation of bacteria. In 2012 he presented thesis entitled
“Conversion of postconsumer polyethylene to biodegradable polymer
polyhydroxyalkanoate” and successfully graduated from UCD with PhD
in industrial microbiology. In the following years he worked in a UCD
spin out company Bioplastech, where he was developing fermentation
strategies for PHA production. He was also a lead on a project aiming at
production of small molecules arising from PHA. In 2015 he moved back
to Kraków, his home town, and become a fellow at J. Haber Institute of
Catalysis and Surface Chemistry PAS. Here he is a PI of several projects
in area of production and application of polyhydroxyalkanoates.
e:
ncguzik@cyfronet.plMater Sci Nanotechnol, Volume: 03