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Pharma Chem Congress 2019
Journal of Pharmaceutical Chemistry & Chemical Science | Volume 3
June 12-13, 2019 | Bangkok, Thailand
OF EXCELLENCE
IN INTERNATIONAL
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alliedacademies.comYEARS
PHARMACEUTICAL
CHEMISTRY AND DRUG DISCOVERY
2
nd
International Conference on
J Pharm Chem Chem Sci 2019, Volume 3
APPLICATION OF THE STANDARDIZED FORM MAGNETITE NANOPARTICLES (ICNB) IN
CREATURE SIMPLE AND PRACTICAL METHOD OF ADDITIVE MODERNIZATION OF PRES-
ERVATION SOLUTIONS FOR RED BLOOD CELLS
Andrey Belousov
1, 2, 3
, Elena Malygon
2, 3
, VadimYavorskiy
2, 3
and
Ekateryna Belousova
1, 3
1
Laboratory of Applied Nanotechnology of Belousov, Ukraine
2
Kharkov Medical Academy of Postgraduate Education, Ukraine
3
Kharkov Regional Center of Blood Service, Ukraine
T
his study was devoted to the learning of the use of nanotechnology to correct the functional activity of red
blood cells (RBCs) at the storage stages at a positive temperature. It was established that saline NaCl, which
had previously been processed by magnetite nanoparticles (ICNB) had a marked membrane-stabilizing effect,
inhibits hemolysis and increasing the sedimentation stability of preserved RBCs. The complex analysis of the
obtained data allowed determining the primary mechanisms effect of the saline NaCl, which had previously
been processed by ICNB on the preserved RBCs. The proposed method of additive modernization of preserved
RBCs was adapted to the production process. The optimization results were obtained in creating a simple and
practical method of additive modernization of preservation solutions that does not violate the compliance
requirements, improves the quality, efficiency and safety transfusion of RBCs.