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Journal of Current Pediatric Research | Volume: 23
March 14-15, 2019 | London, UK
International Conference on
Pediatrics & Neonatal Healthcare
Blood product transfusion and postoperative outcome in Pediatric Neurosurgical patients
Claudine Kumba, Taright H, Terzi E, Telion C, Beccaria K, Paternoster G, Zerah M, Bustarret O, Jugie M, Rubinsztajn R
and
Treluyer JM
Necker Enfants Malades University Hospital, France
Background:
Intraoperative and postoperative Morbi-
mortality factors are multiple in pediatric patients. Studies
in pediatric cardiac surgery and intensive care patients have
identified transfusion one factor among others. This study was
undertaken to investigate whether transfusion was a risk factor
of postoperative outcome in neurosurgical pediatric patients.
Objectives:
To identify Morbi-mortality risk factors in
intraoperatively transfused and not transfused pediatric
neurosurgical patients.
Design:
Retrospective observational descriptive pediatric
cohort study.
Setting:
Monocentric pediatric tertiary center, Necker Enfants
Malades University Hospital Paris, from 1 January 2014 to 17
Mai 2017.
Patients:
206 patients with a median age of 60 months [13.25-
135.75] were included. Inclusion criteria were the presence
or the absence of transfusion in the intraoperative period in
neurosurgery patients. Exclusion criterion was transfusion in
the postoperative period until discharge from hospital.
Main outcome measures:
Primary outcome was mortality
and secondary outcome was morbidity in transfused and
non-transfused patients. Mortality was assessed by deaths
occurring intraoperatively or postoperatively during the entire
hospitalization. Morbidity was assessed by intraoperative,
postoperative complications, repeat surgery, length of stay in
the intensive care unit, in the hospitalization ward, total length
of stay in hospital and length of mechanical ventilation.
Results:
ASA score status (odds ratio 2.49; p-value <0.01) and
transfusion (odds ratio 1.33; p-value 0.03) were predictive risk
factors for complications. Emergency surgery (odds ratio 6.8;
p-value 0.03) was a predictive risk factor for repeat surgery.
ASA score, transfusion and emergency surgery were predictive
risk factors for length of stay in the intensive care unit, total
length of stay in hospital and length of mechanical ventilation
(p-value<0.0001)
EC Anaesthesia 2018; 4(8): 288-298.
Speaker Biography
Claudine Kumba graduated as a Medical Doctor in 2001 and completed her specialization
in Anesthesiology in 2006 at the Free University of Brussels (ULB, Université Libre de
Bruxelles). She has a Paediatric Anaesthesia specialisation graduation since 2010 from
the University of Aix-Marseille, Marseille, France. She has a Critical Care Medicine
specialisation graduation since 2014 from the University of Montpellier 1, Montpellier,
France. She is a paediatric anaesthesiologist in Necker Sick Children’s University Hospital,
in Paris, France. She has 12 publications and 17 citations. She is a member of the European
Society of Paediatric Anaesthesiology (ESPA), the French Society of Anaesthesia and Critical
Care (SFAR, Société Française d’Anesthésie-Réanimation) and the French Association
for Paediatric Anaesthesiolgists and Intensivists) (ADARPEF, Association d’Anesthésistes
et Réanimateurs Pédiatriques d’Expression Française) and the Belgian Association for
Paediatric Anaesthesiology (BAPA).
e:
claudine.kumba@gmail.comNotes:
Claudine Kumba et al.
, Curr Pediatr Res, Volume 23
DOI: 10.4066/0971-9032-C1-011