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April 17-18, 2019 | Frankfurt, Germany

Parkinson’s, Huntington’s & Movement Disorders

International Conference on

Page 16

Notes:

Journal of Brain and Neurology | Volume 3

D

iseases of the central nervous systemmay lead to

severe movement disorders. Parkinson’s Disease

(PD) – one of these disorders - is characterized by

involuntary movement of body parts resulting from

antagonistic muscle contractions. Symptoms of

PD can mostly start to appear at an average age of

59 years. Although there are drugs to manage the

symptoms – albeit potentially life-threatening - and

social approaches to help cope with the disease,

tremor progresses with time and becomes significant

when the patient is elderly. Thus, to help elderly

people who exhibit spatial and temporal movement

variability, a mechanical treatment is suggested.

Tuned vibration absorbers have been studied and

designed to reduce the resting tremor of PD’s

patient when attached to the forearm of the upper

limb. Numerical and simulation studies that are

based on a three degree-of-freedom biodynamic

modeling of the human hand in horizontal plane at

the musculoskeletal level are used to model a system

of flexion-extension planar motion of the shoulder,

elbowandwrist joints. Theperformanceof thesystem

is assessed in terms of the percentage of reduction

in the primary system’s displacement amplitude and

the bandwidth of each designed passive controller.

Speaker Biography

HassanM. Khachfe1 earned a B.S. in Physics,

aM.Sc

. in Polymer Chemistry,

andaPh.D.inBiophysicsandMolecularMedicine.Herunsmultidisciplinary

research projects and supervises two interdisciplinary research groups.

The Lebanese Institute for Biomedical Research and Application

(LIBRA) deals with the structural determination and characterization

of macromolecular assemblies, the analysis of complex signals, and the

design of MEMS/NEMS for biomedical applications. Current projects focus

on understanding the molecular details of the disease-causing plasma

apolipoproteins, Apo B100 of the low density lipoprotein (LDL), on finding

novel approaches for the decontamination and lengthy storage of foods,

and on the design of mechanical absorbers as vibration suppressors for

Parkinson’s patients. Prof. Khachfe also heads the Business, Educational,

and Medical Optimization REsearch (BE-MORE) group, which explores

the design and implementation of automated quality management,

control, assurance, and business systems for healthcare and educational

institutions.

e:

hassan.khachfe@liu.edu.lb

Hassan M Khachfe

Sarah Gebai, Mohamad Hammoud

Lebanese International University, Lebanon

The use of mechanical vibration absorbers to reduce the tremor in

Parkinson’s disease patients