parkinsons-2019-keynote

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allied
academies
April 17-18, 2019 | Frankfurt, Germany
Parkinson’s, Huntington’s & Movement Disorders
International Conference on
Page 16
Notes:
Journal of Brain and Neurology | Volume 3
Diseases of the central nervous systemmay lead to
severe movement disorders. Parkinson’s Disease
(PD) – one of these disorders - is characterized by
involuntary movement of body parts resulting from
antagonistic muscle contractions. Symptoms of
PD can mostly start to appear at an average age of
59 years. Although there are drugs to manage the
symptoms – albeit potentially life-threatening - and
social approaches to help cope with the disease,
tremor progresses with time and becomes significant
when the patient is elderly. Thus, to help elderly
people who exhibit spatial and temporal movement
variability, a mechanical treatment is suggested.
Tuned vibration absorbers have been studied and
designed to reduce the resting tremor of PD’s
patient when attached to the forearm of the upper
limb. Numerical and simulation studies that are
based on a three degree-of-freedom biodynamic
modeling of the human hand in horizontal plane at
the musculoskeletal level are used to model a system
of flexion-extension planar motion of the shoulder,
elbowandwrist joints. Theperformanceof thesystem
is assessed in terms of the percentage of reduction
in the primary system’s displacement amplitude and
the bandwidth of each designed passive controller.
Speaker Biography
HassanM. Khachfe1 earned a B.S. in Physics, . in Polymer Chemistry,
andaPh.D.inBiophysicsandMolecularMedicine.Herunsmultidisciplinary
research projects and supervises two interdisciplinary research groups.
The Lebanese Institute for Biomedical Research and Application
(LIBRA) deals with the structural determination and characterization
of macromolecular assemblies, the analysis of complex signals, and the
design of MEMS/NEMS for biomedical applications. Current projects focus
on understanding the molecular details of the disease-causing plasma
apolipoproteins, Apo B100 of the low density lipoprotein (LDL), on finding
novel approaches for the decontamination and lengthy storage of foods,
and on the design of mechanical absorbers as vibration suppressors for
Parkinson’s patients. Prof. Khachfe also heads the Business, Educational,
and Medical Optimization REsearch (BE-MORE) group, which explores
the design and implementation of automated quality management,
control, assurance, and business systems for healthcare and educational
institutions.
e:
Hassan M Khachfe
Sarah Gebai, Mohamad Hammoud
Lebanese International University, Lebanon
The use of mechanical vibration absorbers to reduce the tremor in
Parkinson’s disease patients