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Journal of Research and Reports in Gynecology and Obstetrics | Volume: 3
February 28-March 01, 2019 | Paris, France
Palliative Care, Obstetrics and Gynecology
Stroke and Clinical Trials
International Conference on
Joint Event on
International Conference on
&
M
agnetic Nanofluid Hyperthermia (MNH) has been
recently paid an enormous attraction as a Renaissance of
cancer treatment modality particularly, due to its prominently
low side effects and high treatment efficacy compared to
conventional chemotherapy and radiotherapy. However,
insufficient ACmagnetic induction heating power at a biological
safe range of AC magnetic field (H
appl
x f
appl
< 3.0 ~ 5.0 x 10
9
Am
-
1
s
-1
), and highly required
in-vitro
&
in-vivo
biocompatibility as
well as biocleanrance with chemical suspension stability of
superparamagnetic nanoparticle (SPNP) hyperthermia agents
are still remained as critical challenges for successful clinical
hyperthermia applications. In addition, an automatically and
accurately controllable AC magnetic induction heat generator
for mid or large-sized animals including human patients are
essentially required for highly efficient hyperthermia in cancer
clinics.
Total solution of Magnetic Nanofluid Hyperthermia (MNH) by hypertheranoid
TM
system to
treat solid cancers with exceptionally high treatment efficacy
In this talk, I will present the newly developed highly
biocompatible magnesium shallow doped γ -Fe
2
O
3
nanofluids
(hypertheranoid
TM
-1) with exceptionally high intrinsic loss
power (ILP) in a range of 14 nhm
2
kg
-1
, which is a ~100 times
higher than that of commercial Fe
3
O
4
(Feridex, ILP = 0.15
nhm
2
kg
-1
) at a H
appl
x f
appl
= 1.23 x 10
9
Am
-1
s
-1
, and also report our
newly commercialized hyperthereanoid
TM
-EX AC magnetic field
generators, which produce automatically controlled precise AC
magnetic field, for small animal pilot studies, formid-size animal
cancer treatment for veterinary clinc, and for human patients
in cancer clinic.
In-vitro
and
in-vivo
magnetic hyperthermia
studies using various hypertheranoid
TM
-1 nanofluids and
hyperthereanoid
TM
-EX series are conducted to evaluate the
bio-feasibility and bio-availability for preclinical and clinical
applications. According to the all the bioavailability testing
results, it was obviously verified that the newly developed
hyperthereanoid
TM
system shows promising hyperthermic
effects to completely kill the solid cancers.
Speaker Biography
Seongtae Bae received his Ph. D degree in Electrical and Computer Engineering from the
University of Minnesota, Minneapolis, USA in 2003. He is currently working as an assistant
professor and a director of “Nanobiomagnetics and Bioelectronics Laboratory (NB2L)”
in the Department of Electrical Engineering at the University of South Carolina (USC),
Columbia, USA. And also, he has a joint appointment with biomedical engineering program
in the college of engineering and computing at USC, he was also an associate professor in
department of neurosurgery at the Seoul National University (SNU) college of medicine,
Seoul, Korea and National University of Singapore (NUS) (Singapore) for 9 years. His
current research interests are focused on magnetic nanofluids for cancers,
in vivo
&
in-vitro
magnetic based biosensors/biomems, extremely low frequency nanomagnetic biomedical
devices and medical instrumentation for neural engineering (neurodegenerative diseases/
neuromodulation). He is currently members/board member/editorial board member of
IEEEMagnetics Society, IEEE Engineering inMedicine and Biology Society, American Physics
Society (APS), Korean Society for Nanomedicine, International Society of Hyperthermic
Oncology, and EC Ophthalmology.
e:
Bae4@cec.sc.eduSeongtae Bae
University of South Carolina, USA
Colossal magnetic heat induction of magnesium doped γ-Fe
2
O
3
nanofluids
(hypertheranoid
TM
-1) and highly efficient AC magnetic field generator system
(Hypertheranoid EX
TM
) for thermoablation of cancers
Seongtae Bae
, Res Rep Gynaecol Obstet, Volume 3
DOI: 10.4066/2591-7366-C1-001