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Otolaryngology 2019 Otolaryngology Online Journal | ISSN: 2250-0359 | Volume 9
Page 12
July 18-19, 2019 | Valencia, Spain
OTOLARYNGOLOGY: ENT SURGERY
8th Global Summit on
OF EXCELLENCE
IN INTERNATIONAL
MEETINGS
YEARS
ONCOLOGIC EFFICACY OF KTP LASER IN
EARLY GLOTTIC CANCER
Background: Early glottic cancer (T1, T2) is typically managed by cura-
tive-intent radiotherapy or CO2 laser resection. Disease control rates and
voice outcomes are comparable. KTP laser treatment of early glottic can-
cer has shown promise with similar control rates in limited studies. This
study presents the largest series outside its conception in Boston, USA.
Methodology: A retrospective chart review analyzed treatment out-
come of consecutive patients with early glottic cancer (T1-2 NOMO).
Pre-treatment videostroboscopy and voice handicap index were com-
pared two years following treatment. Recurrence, progression to radia-
tion or open surgery and mortality were recorded.
Results: For 61 patients (average age 61 years, 59 males) 34=T1a,
15=T1b, 9=T2a and 3=T2b. Three had prior irradiation and were exclud-
ed. Four patients had recurrence (6.9%): Two CIS (treated with repeat KTP
laser surgery), two SCC (one recurrence progressed to open partial resec-
tion and chemoradiotherapy with subsequent total laryngectomy for a
non-functioning cancer-free larynx, one recurrence progressed to total
laryngectomy within one year and then chemotherapy for extensive lo-
co-regional recurrence three months later. Primary KTP laser treatment
provided 100% disease-free survival at two years, larynx preservation of
96.5% and post-surgery radiation at 2%. Radiotherapy was preserved as
a future option in 98% of patients (100% in T1, 91.6% of T2). The cure rate
was 96.5% (Two year minimum follow-up).
Conclusion: This study provides further data supporting oncological ef-
ficacy of KTP laser treatment in early glottic cancer. Recurrence and sal-
vage total laryngectomy rates are low with the former often amenable
to repeat KTP laser treatment. There is minimal requirement for post-sur-
gery radiation allowing its preservation as a future treatment in 98%.
Matthew S Broadhurst, Otolaryngology Online Journal 2019, Volume 9
Matthew Broadhurst is a fellowship trained la-
ryngeal and upper airway surgeon specializing
in laryngeal surgery, voice restoration and ob-
structive sleep apnoea. He returned to Brisbane,
Australia from Boston, Massachusetts in 2007
having worked for two years at Harvard Medical
School and Massachusetts General Hospital. He
was the first fellowship trained laryngeal surgeon
in Australia and now has a large tertiary referral
practice in voice and larynx disorders and sleep
apnoea. In his practice, he utilizes state of the
art techniques in surgery to the airway and is ac-
tively involved in clinical research and education
both nationally and internationally. His areas of
special interest and research include KTP laser
for dysplasia and glottic cancer, short and long
termmanagement of vocal fold paralysis, phono-
traumatic lesions in professional voice users and
laryngeal papilloma.
Matthew S Broadhurst
Queensland Voice Centre, Australia
BIOGRAPHY