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academies
17
th
International Conference on
4
th
International Conference on
NEUROLOGY AND NEUROSCIENCE
&
MENTAL HEALTH AND PRIMARY CARE
October 16-18, 2017 | Toronto, Canada
J Neurol Neurorehabil Res 2017 | Volume 2 Issue 3
The effect of subthalamic nucleus deep brain stimulation on dyspepsia symptoms
Atilla Yilmaz
1
, Yucetas Cem
2
and
Ugur Mustafa
1
1
Mustafa Kemal University, Turkey
2
Adiyaman University, Turkey
P
arkinson’s disease (PD) is a progressive neuro-
degenerative disease and characterized by motor and
nonmotor symptoms. Gastrointestinal symptoms like
constipation and dyspepsia are common symptoms in PD.
These symptoms can cause to significant morbidity. The
patients often need to use several medications like antacids,
proton pump inhibitors or H2 receptor blockers for long
term. The beneficial effect of Deep Brain Stimulation (DBS)
has proved by several studies. Subthalamic Nucleus (STN)
and Globus Pallidus Internus GPI) are preferred targets for
PD. There are several studies about the effect of STN-DBS
on motor symptoms, but the studies about the nonmotor
symptoms are limited. Our goal is to evaluate the effect of
STN-DBS on functional dyspepsia. A total 25 patients (sixteen
men and nine women), who underwent bilateral STN-
DBS implantation between April 2016 and May 2017 were
enrolled in this study. The median age was 57 years (range
38–80). The dyspepsia symptoms were evaluated before
and three months after the surgery. Rome III criteria were
used to diagnose the dyspepsia, postprandial bloating and
epigastric complaints. The medications for these complaints
are evaluated to. One patient was excluded because of the
distal esophagus thickening diagnosis. Prior to surgery in
21 patients, at least one of these findings was observed.
17 (68%) patients were using medication regularly. In this
patient group, postoperative evaluation was made on third
month. 3 (17.6%) patients reported that they didn’t feel any
improvement on their complaints. In 5 (29.4%) patients,
improvement and decrease in medication was detected.
In 9 (52.9%) patient’s improvement was detected and
they reported that they don’t need to take medication for
dyspepsia anymore. Our results suggest that the bilateral
STN-DBS surgery improves the dyspepsia complaints as well
as life quality in Parkinson’s disease patients.
Speaker Biography
Yilmaz Atilla is currently an Assistant Professor at the Neurosurgery Department at
Mustafa Kemal University. From 2015, he has served as a Clinical Fellowship in Koc
University College of Medicine and Spine Centre, Istanbul, Turkey and as an Observer
in Florida University Movement Disorder Centre, Gainesville, USA in 2016 and 2017. He
has published more than 10 peer-reviewed journals and 100 conference papers. He is a
Reviewer and Editorial Board Member for several journals in the field of Neurosurgery.
He has also been invited as a speaker of many international conferences. His major
research interests are: functional neurosurgery, neuromodulation and spine surgery.
He also has a lot of experience about war surgery.
e:
atillayilmaz@hotmail.com