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Neuro Congress 2019
Journal of Brain and Neurology | Volume 3
June 19-20, 2019 | Dublin, Ireland
OF EXCELLENCE
IN INTERNATIONAL
MEETINGS
alliedacademies.comYEARS
NEUROLOGY AND BRAIN DISORDERS
3
rd
International Conference on
LONG TERM CONSEQUENCES OF BRAIN TRAUMA IN MICE
Christophe Pellegrino
Aix Marseille University, France
B
rain trauma is the main cause of disability all over the world with a very high prevalence in developed coun-
tries (Meyer
et al
., 2008; Bondi
et al
., 2015). According to the World Health Organization and the Centers for
Disease Control and Prevention (Meyer
et al.
, 2008), brain trauma classification is based on multiple factors
such as altered neurological functions, brain area of interest and genetic variations. Altogether, these factors
lead to highly individualized injuries. Sequels of trauma include low prevalence post-traumatic epilepsies, with
a severity and occurrence dependent on trauma severity (Kelly
et al
., 2015; Bragin
et al
., 2016), cognitive dys-
functions and depression like phenotypes are also commonly associated. Author’s interest focuses on the early
events happening both at cellular and neuronal network level leading to long-term consequences of brain
trauma. They put a particular emphasis in investigating the role of GABAergic transmission in the settling up
of the post-traumatic depression. They have identified the first post-traumatic week as an optimal therapeutic
window. Their rationale is to treat animals before the establishment of the depression in a prophylactic manner.
Christophe Pellegrino, J Brain Neurol 2019, Volume 3
Christophe Pellegrino completed in PhD in Neurosciences in 2009 at Aix Marseille University, France. He worked on neuronal sur-
vival and on the role of intracellular cascades leading to synaptic plasticity of NMDA receptors. Later on he focused on the effect
of brain trauma at cellular and network levels with a particular emphasis on epilepsy and psychiatric disorders such as anxiety and
depression. His publication H-index is 17 and he is involved in reviewing activity of reputed journals. He is teaching neurosciences
and physiology at Aix Marseille University.
christophe.pellegrino@inserm.frBIOGRAPHY