infectious-diseases-congress-2019-keynote

Infectious Diseases Congress 2019

Journal of Bacteriology and Infectious Diseases | Volume 3

Page 22

June 12-13, 2019 | Bangkok, Thailand

BACTERIOLOGY AND INFECTIOUS DISEASES

Global Congress on

OF EXCELLENCE

IN INTERNATIONAL

MEETINGS

YEARS

SELF-ADJUVANTING LIPOPEPTIDE

NANOPARTICULATE VACCINE

CANDIDATES FOR THE INDUCTION OF

PROTECTIVE IMMUNE RESPONSES

djuvants are essential for enhancing and directing the adaptive

immune response to vaccine antigens. The relationship between a

vaccines physicochemical property and the type of immune response

acquired is critical for the advancement of vaccine adjuvants. This un-

derpins researcher’s goal to study the structure-activity relationship be-

tween self-adjuvanting lipid-based vaccine candidates containing oval-

bumin (OVA) CD4 and CD8 peptide epitopes to determine the optimal

architecture for stimulation of potent cell-mediated immune responses.

Constructs that formed small nanoparticles showed higher cytolytic ac-

tivity and enhanced tumour growth inhibition. Overall the investigation

of the relationship between physicochemical properties self-assembled

nanoparticles and immune response for new vaccine candidates is very

important.

Istvan Toth, J Bacteriol Infec Dis 2019, Volume 3

Istvan Toth is a Chemical Engineer and an inter-

nationally recognized expert in drug delivery.

His major research interests lies in immunoad-

juvants, carbohydrates, lipids, peptides, nucleo-

sides and nucleotides. He is a Fellow of the Royal

Australian Chemical Institute, The Queensland

Academy of Science and Art and The Hungarian

Academy of Sciences.

Istvan Toth

The University of Queensland, Australia

BIOGRAPHY