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J Gastroenterol Dig Dis 2017 | Volume 2, Issue 3
World Gastroenterological &
Gastroenterology and Endoscopy
October 30-31, 2017 | Toronto, Canada
World Congress on
Non endoscopic predictors of esophageal varies
Dipak Baral
Life Line Hospital Jhapa Nepal, Nepal
Background:
Esophageal varices are serious consequence
of portal hypertension in patient with liver diseases. The
objective of this research was to assess the diagnostic
efficiency and usefulness of non-invasive markers of cirrhosis
in the context of esophageal varices.
Methods:
This cross sectional study was conducted in
NAMS, Bir Hospital among 64 patients who met the selection
criteria. After randomization, they were subjected to a
screening endoscopy and a blood analysis. SPSS statistical
analysis software was use to analyze data. T-test and one
way ANOVA were used to find mean differences, and ROC
curves were used to establish cutoff points.
Results:
Out of 64 patients, majorities were of age group 50-
60 years and the mean age was 51.2±9.6 years. Most of the
cases presented in Child Pugh’s Class A, and 70% of them
have Ascites on presentation. Oesophageal varices were
detected in 59% and 71% of male and female patients on
screening endoscopies respectively. Mean platelet counts,
serum albumin levels were significantly lower and splenic
diameter was significantly higher (138.7±19.73). The platelet
count / splenic diameter ratio was significantly lower with
both the occurrence of varices and the severity of varices
as compared to patients without varices (746.2 ±201.3 and
1562±322.4) (with a significant p<0.05) respectively.
Conclusion:
The findings of this study suggest that non-
invasive and non-endoscopic markers like Platelet count,
Serum Albumin Levels, Splenic Diameter and the Platelet
count/splenic diameter ratio can be used as markers to
detect the presence of esophageal varices in patients that
do not undergo UGI endoscopy.
Speaker Biography
Dipak Baral has completed MD from Bir Hospital, NAMS, Kathmandu, Nepal and
interventional endoscopy from Kathmandu University. He is the Member of European
Society of Gastrointestinal Endoscopy. He is working currently as a Consultant Physician
and Endoscopist at Life Line Hospital Jhapa Nepal. He has several publications in
international journal.
e:
dipak_baral@hotmail.com