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September 05-06, 2019 | London, UK
7th International Conference on
2nd International Conference on
Otolaryngology: ENT Surgery
Dental Health and Oral Hygiene
Joint Event
&
Otolaryngology Online Journal | ISSN: 2250-0359 | Volume 9
The sensitivity and specificity of the extra tympanic electrocochleography (ECochG)
in Meniere’s disease
M-Basel Alassi
Emirates Hospital, Dubai
Background: Electrocochleography (ECochG) is one of
the tests used in the diagnoses, monitoring and follow-up
of patients with Meniere’s disease (MD). Extra-tympanic
ECochG is a non-invasive method to record the amplitude
of summating potential (SP) alone or the amplitude ratio
of SP and action potential (AP) and conclude the AP/SP
amplitude ratio.
Objectives: The study aimed to study the SP and AP
amplitude and the SP/AP amplitude ratio in individuals
with normal hearing and in those with definite Meniere’s
disease, and to conclude the sensitivity and the specificity of
the ECochG test in differentiating the patients of Meniere’s
disease from normal people.
Materials and Methods: In this retrospective chart review,
the study population is composed of 25 subjects (35 ears),
consisted of 18 ears of 10 normal people and 17 ears of
15 definite Meniere’s disease patients. Extra-tympanic
non-invasive ECochG recording was done for all the
participants.
Results: The measurements of the mean SP latency, SP
amplitude, AP latency, AP amplitude and SP/AP amplitude
ratio in the normal individuals group are: (0.92msec, SD=0.2),
(0.18μV, SD=0.12), (1.55 msec, SD=0.18), (0.18μV, SD=0.12),
(1.03μV,SD=0.69)and(SP/APratio=0.21,SD=0.09)respectively.
While the Meniere’s disease individuals group showed values
of (0.98 msec, SD=0.27), (1.09μV, SD=2.83), (1.58 msec,
SD=0.29), (0.86μV, SD=0.62) and (SP/AP ratio=0.45, SD=0.15)
respectively. There was no significant difference between
the two groups in the values of SP latency, SP amplitude, AP
latency and AP amplitude. The SP/AP amplitude ratio values
of both groups revealed a significant difference between the
two groups (p<0.00001). The study also concluded the values
of The ECochG sensitivity (88%), ECochG Specificity (94%).
Conclusion: The elevation of the SP/AP amplitude rate
of the ECochG test is a powerful method to discriminate
between Normal individuals and Meniere’s disease patients.
Extratympanic ECochG has a high sensitivity (88%) and high
specificity (94%) in the diagnosis of definiteMeniere’s disease
patients.
e:
Otolaryngology online
Volume: 9