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June 24-25, 2019 | Philadelphia, USA
DIABETES, ENDOCRINOLOGY, NUTRITION
AND NURSING MANAGEMENT
2nd International Conference on
Diabetes Congress 2019 Journal of Diabetology | Volume 3
Page 16
OF EXCELLENCE
IN INTERNATIONAL
MEETINGS
YEARS
COMPARISON OF GLUCOSE DATA AND
PHENOMENA FROM TWO DIFFERENT
MEASUREMENT METHODS (GH-METHOD:
MATH-PHYSICAL MEDICINE)
Introduction: This paper discusses glucose measurement results from two
different methods, finger piercing and testing strip (Finger) and Libre’s con-
tinuous glucose monitoring system (Sensor).
Method: The author has been collecting a total of 9,490 glucose data by fin-
ger measurement, including both fasting plasma glucose (FPG) once a day
since 1/1/2014 (1,825 days) and postprandial plasma glucose (PPG) three
times a day since 1/1/2012 (2,555 days). Recently, he has further collected
17,046 glucose data by applying a sensor on his upper arm to collect his
glucose values continuously. This sensor measurement is conducted in par-
allel with his routine finger measurements. During the period of 5/5/2018
to 12/31/2018 (241 days), he has recorded his sensor glucose values about
71 times per day. The measurement rate is approximately every 15 minutes
during the day and every hour during the night. In summary, he has col-
lected a total of 964 waveforms- 241 FPG and 723 PPG. Other waveforms
generated between meals or from eating snack/fruit are not included in this
analysis.
Results: Sensor’s time of peak glucose: 60 minutes after first-bite; PPG rising
speed: 33 mg/dL per hour; PPG decaying speed: 20 mg/dL per hour (~60%
of rising); Finger’s average FPG/PPG: 110/116 mg/dL (as 100% baseline); Sen-
sor’s peak PPG & % over finger: 159 mg/dL & 138% (+43 mg/dL); Sensor’s
average PPG & % over Finger: 135 mg/dL & 117% (+19 mg/dL); FPG (period-
from 00:00 to 07:00): Average FPG: 112 mg/dL; Peak (crest): 122 mg/dL; Valley
(trough): 106 mg/dL; Period of trough (from 3am to 5am).
Conclusion: In average, PPG peak occurs one hour after first-bite of meal, not
two hours after; PPG decaying speed is almost twice as slow than its rising
speed; Averaged sensor’s PPG is 16% higher (+19 mg/dL) than the Averaged
finger’s PPG; Peak sensor’s PPG is 36% higher (+42 mg/dL) than the Averaged
finger’s PPG; FPG wave is much calmer than PPG wave and FPG’s lowest
trough range occurs during the deep sleep stage (from 3am to 5am).
Gerald C Hsu has completed his PhD in Mathe-
matics and has been majored in Engineering at
MIT. He has attended different universities over
17 years and studied seven academic disciplines.
He has spent 20,000 hours in T2D research. First,
he studied six metabolic diseases and food nutri-
tion during 2010-2013, then conducted research
during 2014-2018. His approach is math-physics
and quantitative medicine based on mathe-
matics, physics, engineering modeling, signal
processing, computer science, big data analyt-
ics, statistics, machine learning and AI. His main
focus is on preventive medicine using prediction
tools. He believes that the better the prediction,
the more control you have.
Gerald C Hsu
EclaireMD Foundation, USA
BIOGRAPHY
Gerald C Hsu, J Diabetol 2019, Volume 3