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J Nutr Hum Health 2017 Volume 1 Issue 2
Notes:
July 24-26, 2017 | Vancouver, Canada
International conference on
DIABETES, NUTRITION, METABOLISM & MEDICARE
Background:
Currently, low-fat diet is mainly recommended
in America and China [1]. However, the diet among T2DM
are not complete accordance to the recommended protocol.
Low-Carbohydrate Diet (LCD) achieved greater improvement
in the lipid profile and blood glucose stability compared to
low-fat diet [2]. In addition, food rich in carbohydrate were
preferred by Chinese. It is worth of exploring the feasibility
and effect of LCD in Chinese DM patients.
Methods:
We total enrolled 31 T2DM patients according to
inclusion and exclusion. They were intentionally grouped
into LCD group (N = 18) and Low-Fat Diet (LFD) group (N =
20).LFD group received regular loose LFD education (Six
points Formulas); LCD group received loose LCD(Six points
Formulas) education. After three months, we compared the
percentage of energy from three macronutrients, HbA1c,
BMI, TC, TG, LDL-C, HLD-C, insulin dose, the frequency of
hypoglycemia.
Results:
(1) Adherence to LCD and LFD There were three
patients missing or excluded in LCD group: one could not
completeLCD, onewasout-of-touchandanother experienced
appendectomy. However, four patients could not complete
diet regimen in LFD group. (2) The percentages of energy
from three macronutrients The percentages of energy from
three macronutrients in LCD and LFD after intervention were
all met the definition of LCD and LFD. (3) HbA1c The levels of
HbA1c between intra-group in two group were significantly
decreased (4) Lipids profile Compared with baseline, BMI,
TG and HDL - C in LCD group were improved significantly
after the intervention(P<0.01); while BMI only was improved
in LFD group(P<0.01). After the intervention, the serum
lipids profile had no difference between groups. (5) Insulin
dose There were significantly reduced doses of insulin after
intervention in both of groups (6) Hypoglycemia After the 3
months interventions, the frequency of hypoglycemia in LCD
group has decreased significantly, compared to the baseline
(P<0.05). In LFD group, the frequency of hypoglycemia had
no significant change.
Discussion:
LCD intervention is feasible and easy-operated/
practical for the Chinese T2DM patients. It can effectively
improve blood glucose, blood lipid and BMI. At the same time,
it can reduce the dosage of insulin in patients with T2DM
for the short term. This strategy should be recommended in
Chinese T2DM patients.
Biography
Xiao Hua Wang has completed her PhD majored in immunology from Soochow
University. She has been the director of Medical Nursing over ten years. She has
published more than 30 papers in impact journals and has been serving as a reviewer
of some journals.
sxwang2001@163.comEffect of low carbohydrate diet on metabolism in patients with type 2 diabetes mellitus
Xiao Hua Wang
1, 2
and
Qi Wang
1
1
The Division of Cardiology, the First Affiliated Hospital of Soochow University, Suzhou, China
2
School of Nursing, Soochow University, Suzhou, China