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J Nutr Hum Health 2017 Volume 1 Issue 2

Notes:

July 24-26, 2017 | Vancouver, Canada

International conference on

DIABETES, NUTRITION, METABOLISM & MEDICARE

Background:

Currently, low-fat diet is mainly recommended

in America and China [1]. However, the diet among T2DM

are not complete accordance to the recommended protocol.

Low-Carbohydrate Diet (LCD) achieved greater improvement

in the lipid profile and blood glucose stability compared to

low-fat diet [2]. In addition, food rich in carbohydrate were

preferred by Chinese. It is worth of exploring the feasibility

and effect of LCD in Chinese DM patients.

Methods:

We total enrolled 31 T2DM patients according to

inclusion and exclusion. They were intentionally grouped

into LCD group (N = 18) and Low-Fat Diet (LFD) group (N =

20).LFD group received regular loose LFD education (Six

points Formulas); LCD group received loose LCD(Six points

Formulas) education. After three months, we compared the

percentage of energy from three macronutrients, HbA1c,

BMI, TC, TG, LDL-C, HLD-C, insulin dose, the frequency of

hypoglycemia.

Results:

(1) Adherence to LCD and LFD There were three

patients missing or excluded in LCD group: one could not

completeLCD, onewasout-of-touchandanother experienced

appendectomy. However, four patients could not complete

diet regimen in LFD group. (2) The percentages of energy

from three macronutrients The percentages of energy from

three macronutrients in LCD and LFD after intervention were

all met the definition of LCD and LFD. (3) HbA1c The levels of

HbA1c between intra-group in two group were significantly

decreased (4) Lipids profile Compared with baseline, BMI,

TG and HDL - C in LCD group were improved significantly

after the intervention(P<0.01); while BMI only was improved

in LFD group(P<0.01). After the intervention, the serum

lipids profile had no difference between groups. (5) Insulin

dose There were significantly reduced doses of insulin after

intervention in both of groups (6) Hypoglycemia After the 3

months interventions, the frequency of hypoglycemia in LCD

group has decreased significantly, compared to the baseline

(P<0.05). In LFD group, the frequency of hypoglycemia had

no significant change.

Discussion:

LCD intervention is feasible and easy-operated/

practical for the Chinese T2DM patients. It can effectively

improve blood glucose, blood lipid and BMI. At the same time,

it can reduce the dosage of insulin in patients with T2DM

for the short term. This strategy should be recommended in

Chinese T2DM patients.

Biography

Xiao Hua Wang has completed her PhD majored in immunology from Soochow

University. She has been the director of Medical Nursing over ten years. She has

published more than 30 papers in impact journals and has been serving as a reviewer

of some journals.

sxwang2001@163.com

Effect of low carbohydrate diet on metabolism in patients with type 2 diabetes mellitus

Xiao Hua Wang

1, 2

and

Qi Wang

1

1

The Division of Cardiology, the First Affiliated Hospital of Soochow University, Suzhou, China

2

School of Nursing, Soochow University, Suzhou, China