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April 11-12, 2019 | Barcelona, Spain
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alliedacademies.comYEARS
Dermatology 2019
Research in Clinical Dermatology | Volume 2
3
rd
WORLD DERMATOLOGY
AND COSMETOLOGY CONGRESS
THE EFFECTIVENESS OF TWO ORIGINAL LIQUID CRYSTAL FORMULATIONS WITH
RETINOL IN RANDOMIZED PARALLEL CONTROL TRIAL
Malwina Zasada
Medical University of Lodz, Poland
V
itamin A is the first vitamin approved by FDA (Food and Drug Administration) in treating wrinkles, fine
lines, changes in micro relief and anti-aging effects. We sought to evaluate the efficiency and tolerability
of treating signs of aging skin like wrinkles, hyperpigmentation’s and uneven surface of the skin using a 0.15%
and 0.3% retinol. Patients at 2 sites (n=20, n=20) applied a novel formulation of retinol respectively 0.15% on
the left and 0.3% on the right, daily to their faces for 2 months. Expert blind evaluation of images (VAS, visual
analogue scale) occurred at week 4 and week 8. Tolerability was assessed throughout the study. Positive results
of the observed pilot study warranted a follow-up study on the higher concentration and other parallel study.
Most participants showed improvement in overall skin condition, which were graded at week 4 and week 8.
Improvements at 56 days were comparable on the left and right side. The pilot study was crucial to evaluate
the effects of two different concentrations in one original formulation to check if concentration in cosmetic
products indicates visible changes in treatment.
Malwina Zasada, Res Clin Dermatol 2019, Volume 2
Malwina Zasada is attending third year of PhD study at Medical University of Lodz. She is an author of impact factor publications; she
also takes part in national and International conferences. She is a Manager in cosmetic brand where she is responsible for training
and science field, sharing her knowledge about cosmetology and chemistry. She participated in medical studies since bachelor
degree and created new liquid crystal cosmetic formulation, checking if retinol could give the same results in lower concentration
compared to higher in biomimetic cosmetic base.
malwina.zasada@gmail.comBIOGRAPHY