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Journal of Medical Oncology and Therapeutics | Volume 4
February 25-26, 2019 | Paris, France
13th World Cancer Congress
In general the scientific literature reports that aging favors
the development of cancers. Each type of cancer however,
initiates and evolves differently and their natural history can
startway back at earlier ages before their clinicalmanifestations.
The incidence of cancers is spread through the human life span,
it is the result of pre- and post-natal aggressions, individual
susceptibility, and developmental changes that evolve
continuously from the beginning to the end. Finally during
human senescence the incidence declines for all cancers.
Frequently the progression of cancers is also slower in the old.
There are several possible explanations for this decline at the
tissue, cellular, and molecular levels. It is time to ask why some
tumors are characteristic of the young, others of maturity,
others of the time of the decline of the reproductive period,
and finally why the incidence of cancers declines late during
senescence of the human organism. These questions should be
answered before the origin of cancers can be understood.
Speaker Biography
Alvaro Macieira-Coelho is a Research Director at the French National Institute of
Health. He received an MD from the University of Lisbon, Portugal, and a PhD from
the University of Uppsala Sweden. He made an internship at the University Hospital in
Lisbon and was a research associate at the Wistar Institute in Philadelphia (USA) and
at the Department of Cell Biology of the University of Uppsala (Sweden). He became
Head of the Department of Cell Pathology at the Cancer Institute in Villejuif (France)
and was a visiting Professor at the University of Linkoping (Sweden). He published
150 papers in professional Journals and 9 books on cancer and aging. He received the
following awards: Fritz Verzar Prize (University of Vienna, Austria), “Seeds of Science”
Career Prize (Lisbon, Portugal), Dr. Honoris Causa (University of Linkoping, Sweden),
Johananof International Visiting Professor (Institute Mario Negri, Milano, Italy).
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Alvaro Macieira-Coelho
French National Institute of Health, France
The decline of the prevalence of Cancers during organism senescence