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December 05-06, 2019 | Dubai, UAE

29

th

International Conference on

14

th

International Conference on

Nursing Education and Research

Cancer and Cancer Therapy

Joint Event

&

Journal of Medical Oncology and Therapeutics | Volume 4

Notes:

Prostate Cancer new approaches and treatments from the quality of life perspective

Haluk Kulaksizoglu

A A Medical Center Dubai, UAE

Aim:

Overthelast5yearstheunderstandingofprostatecancer

behavior, improvement in technologies relating to diagnostic

techniques, better surgical and radiotherapy methods and

new emerging drugs have pushed us to changing our insight

to prostate cancer. The aim in this talk is to give an overview

of new clinical applications and techniques that improve life-

span as well as the quality of life in both the patients and their

spouses.

Method:

The presentation is based on relevant scientific data

available relating to changes that occurred over the last few

years in diagnosis, treatment and follow-up of prostate cancer

patients.

Findings:

When and how to screen prostate cancer patients

has been a major concern among communities, health care

providers and the related medical societies’ guidelines.

Strategies resulting in overdiagnosis versus un-detection of

malignant tumors are based on the fact that prostate cancer

may not be actually one type of disease but a large spectrum.

Use of imaging has evolved our thinking of screening.

Multiparametric ProstateMRI has given us 2 unique leverage:

(i) we can detect if the PSA elevation is more predictive

of cancer or other pathologies of the prostate gland Pi-

RADS Scoring System (ii) we can do more accurate biopsies

to identify cancer coupling MRI images with transrectal

ultrasound images during biopsy in fusion biopsy systems.

Biomarker studies to improve PSA sensitivity and specifity is

still a work-in-progress. Avoiding unnecessary biopsies and

having an imagery follow-up of suspicious or cancerous cells

increase the quality of life. It is safer for patients to undergo

‘active surveillance’ with new advances. Once at a treatment

phase, robotic surgery is of course the gold standard to

improve patients recovery time, time to catheter removal

and post-surgery erection quality and recovery. Previous

guidelines dictated that patients with tumors limited to the

capsule can only have definitive treatments. New data show

that even in patients with positive lymph node limited to

iliac nodes and T3 patients with no fixation to the rectum are

candidates for surgical tumor removal. Decreasing the tumor

burden with a minimally invasive surgery has been proven

to increase survival. Additional excelling of radiotherapy

techniques also increased in patients with high stage surgeries

aswell as thosewho are not candidates for surgical procedures.

Local radiotherapy results are as promising as surgeries. High

intensity focused ultrasound, cryotherapy options are also

present for patients. Medical therapies have also improved

to include new hormonal approaches, immune therapies

and more targeted anti-neoplastic medical therapies. While

improving treatment results, many of the new regimens are

also aiming at preventing or decreasing many cardiac, bone-

related and sexual dysfunctions. Recovery protocols for erectile

dysfunction are also more effective. Adjunctive therapies such

as low-intensity shockwave therapies, PRP to oral therapies are

expected to give better recovery in a shorter period of time. For

scientific proof of adjunct therapies we need to wait for long-

term results to appear.

Conclusion:

Being one of the major cancers in male, prostate

cancer diagnosis, treatments and follow-up protocols have

been changing rapidly over the last few years. Due to better

diagnostic tools, better surgical technologies and better

innovations in both pharmacotherapy, medical device and

radiotherapy options provide prolonged survival, better

survival-free follow-up and improved quality of life.

Speaker Biography

Haluk Kulaksizoglu is an experienced Professor of Urology with a

demonstrated history of working in the hospital & health care industry.

He is skilled in Prostate Diseases, Andrology, Urodynamic, Medical

Devices, Kidney Stones, and Kidney Cancer. Strong healthcare services

professional with a doctorate focused in medicine from Cerrahpasa

Medical School.

e:

hlkkulaksizoglu@gmail.com

J Med Oncl Ther| Volume 4