Toxicology Impact Factor
Toxicology within the normal redox state of cells can cause toxic effects through the assembly of peroxides and free radicals that damage all components of the cell, including proteins, lipids, and DNA. Oxidative stress from oxidative metabolism causes base damage, also as strand breaks in DNA. Base damage is usually indirect and caused by reactive oxygen species (ROS) generated, e.g. O2− (superoxide radical), OH (hydroxyl radical) and H2O2 (hydrogen peroxide). However, excess ROS production can damage lipids, DNA, and proteins which may cause necrobiosis. ROS-induced damage underpins various oxidative stress-related human diseases and aging. In addition, the cellular antioxidant defenses may decrease during aging which lands up in age-related increase of ROS and oxidative stress. Excess ROS also can activate the proinflammatory signaling pathways and therefore the release of multiple inflammatory mediators, like cytokines, chemokines, eicosanoids, et al. . Therefore, oxidative stress is implicated in the pathogenesis, development, and progression of a sustained inflammatory state.
High Impact List of Articles
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2020 Conference Announcement on Clinical Pharmacy and Clinical Research
Paul insel -
2020 Conference Announcement on Clinical Pharmacy and Clinical Research
Paul insel -
Risk assessment of heavy metals associated with food consumption in Egypt: A pilot study.
Asmaa Bayoumi Issa, Khaled Yasin, Naglaa Loutfy, Mohamed Tawfic Ahmed*Research Article: Journal of Clinical and Experimental Toxicology
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Risk assessment of heavy metals associated with food consumption in Egypt: A pilot study.
Asmaa Bayoumi Issa, Khaled Yasin, Naglaa Loutfy, Mohamed Tawfic Ahmed*Research Article: Journal of Clinical and Experimental Toxicology
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Determination of indoor formaldehyde concentration by portable sol-gel scanometric method.
Zohreh Mehrabadi, Hossein Faghihian, Abdolreza KhajehzadehResearch Article: Journal of Clinical and Experimental Toxicology
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Determination of indoor formaldehyde concentration by portable sol-gel scanometric method.
Zohreh Mehrabadi, Hossein Faghihian, Abdolreza KhajehzadehResearch Article: Journal of Clinical and Experimental Toxicology
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Central mechanisms of acute lithium toxicity: do accumulating data offer a new approach in treatment?
Pinar Yamanturk-Celik -
Central mechanisms of acute lithium toxicity: do accumulating data offer a new approach in treatment?
Pinar Yamanturk-Celik -
Human corneal cells as an in vitro model for toxicological studies of topical ocular drugs.
Ting-Jun Fan -
Human corneal cells as an in vitro model for toxicological studies of topical ocular drugs.
Ting-Jun Fan
Conference Proceedings
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CH4 capture and sequestration for feed, food and farm facilities - The Southeast asian experience
Nervy C Santiago, DVMPosters & Accepted Abstracts: Journal of Clinical and Experimental Toxicology
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CH4 capture and sequestration for feed, food and farm facilities - The Southeast asian experience
Nervy C Santiago, DVMPosters & Accepted Abstracts: Journal of Clinical and Experimental Toxicology
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Psoriasis - New methods of treatment
Dominika Bielinska-WarezakScientific Tracks Abstracts: Journal of Dermatology Research and Skin Care
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Psoriasis - New methods of treatment
Dominika Bielinska-WarezakScientific Tracks Abstracts: Journal of Dermatology Research and Skin Care
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EVALUATION OF KEY FACTORS IN IMPLANT SYSTEM SELECTION BETWEEN DENTISTS
Mohsen Maleki GorjiPosters & Accepted Abstracts: Journal of Clinical Dentistry and Oral Health
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EVALUATION OF KEY FACTORS IN IMPLANT SYSTEM SELECTION BETWEEN DENTISTS
Mohsen Maleki GorjiPosters & Accepted Abstracts: Journal of Clinical Dentistry and Oral Health
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A rare collision of mature cystic teratoma with benign Brenner tumor in ovary
R Rahul Dev Singh, Sunethri Padma and Sai Kumar MaleyPosters & Accepted Abstracts: Journal of Pathology and Disease Biology
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A rare collision of mature cystic teratoma with benign Brenner tumor in ovary
R Rahul Dev Singh, Sunethri Padma and Sai Kumar MaleyPosters & Accepted Abstracts: Journal of Pathology and Disease Biology
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Causes of childhood blindness at National Eye Centre Kaduna, Nigeria from January 2011 to December 2015
Ezinne Ngozika Esther, Nnadi and OnoikhuaPosters & Accepted Abstracts: Ophthalmology Case Reports
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Causes of childhood blindness at National Eye Centre Kaduna, Nigeria from January 2011 to December 2015
Ezinne Ngozika Esther, Nnadi and OnoikhuaPosters & Accepted Abstracts: Ophthalmology Case Reports