Journal of Gastroenterology and Digestive Diseases

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Polyamines

Polyamines area unit low mass open-chain polycations, extremely charged and ubiquitously gift altogether living cells. Interest has been increasing throughout the last thirty years within the naturally voluminous polyamines ptomaine (diamine), spermidine (triamine) and spermine (tetramine), that were incontestible to be concerned in a very sizable amount of cellular processes. as an example, polyamines participate in modulation of body substance structure, factor transcription and translation, polymer stabilization, signal transduction, cell growth and proliferation, migration, membrane stability, functioning of particle channels and receptor-ligand interactions Polyamines appear to exert their role through ionic interactions, attributable to their distinctive structural feature of frequently spaced positive charges.

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