Journal of Diabetology

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Lipid Metabolism:

Lipid metabolism is that the synthesis and also degradation of lipids in cells, involving the breakdown or storage of fats for energy and therefore the synthesis of structural and functional lipids, like those involved within the construction of cell membranes. ... Other sorts of lipids found within the body are fatty acids and membrane lipids. Lipid metabolism begins within the intestine where the ingested triglycerides are weakened into smaller chain fatty acids and subsequently into monoglyceride molecules (see Figure 1b) by pancreatic lipases, enzymes that break down fats after they're emulsified by bile salts. When food reaches the tiny intestine within the sort of chyme, a digestive hormone called cholecystokinin (CCK) is released by intestinal cells within the intestinal mucosa. CCK stimulates the discharge of pancreatic lipase from the pancreas and stimulates the contraction of the gallbladder to release stored bile salts into the intestine. CCK also travels to the brain, where it can act as a hunger suppressant.

Together, the pancreatic lipases and also bile salts break down triglycerides into free fatty acids. These fatty acids are often transported across the intestinal membrane. However, once they cross the membrane, they're recombined to again form triglyceride molecules. Within the intestinal cells, these triglycerides are packaged along side cholesterol molecules in phospholipid vesicles called chylomicrons.

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