Archives of General Internal Medicine

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Drug-Induced Liver Injury

Drug-induced liver injury (DILI) is associate degree uncommon, however doubtless fatal, explanation for disease that's related to prescription medications, OTC drugs, and flavoring and dietary supplements (HDS). DILI has 2 types: intrinsic and individual. Patient, environmental, and drug-related factors could play a task within the pathological process of DILI. within the us, antibiotics and medicament medicine square measure the foremost common drug categories related to DILI, however HDS square measure on the increase as a cause. Management of DILI involves the removal of the sinning agent and therefore the use of N-acetylcysteine for acetaminophen-induced liver injury. Outcomes vary looking on the drug used and kind of liver injury sustained. Pharmacists will play a vital role within the analysis of DILI, particularly in patients taking multiple medications and supplements.

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