Drug Development
Drug development is the process of making a replacement of pharmaceutical drug in the market, once a lead compound has been identified by the method of drug discovery. This process includes research of preclinical studies on microorganisms and animals, filing for regulatory status, like via the US Food and Drug Administration for an investigational new drug to initiate clinical trials on humans, and should include the step of obtaining regulatory approval with a replacement drug application to plug the drug.
Many aspects of drug development specialise in satisfying the regulatory requirements of drug licensing authorities. These generally constitute variety of tests designed to work out the main toxicities of a completely unique compound before first use in humans. It is a legal requirement that an assessment of major organ toxicity be performed (effects on the guts and lungs, brain, kidney, liver and digestive system), also as effects on other parts of the body which may be suffering from the drug (e.g., the skin if the new drug is to be delivered through the skin).
High Impact List of Articles
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Basal ganglia cerebral infarction patient fMRI imaging analysis before and after acupuncture-medicine therapy
Aihong Guo, Fengli Hao, Futai Li, Bingju Wang, Lianfeng Liu, Zhiru Zhao, Chunhong YaoResearch Article: Biomedical Research
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Basal ganglia cerebral infarction patient fMRI imaging analysis before and after acupuncture-medicine therapy
Aihong Guo, Fengli Hao, Futai Li, Bingju Wang, Lianfeng Liu, Zhiru Zhao, Chunhong YaoResearch Article: Biomedical Research
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Experimental study on effect of calcitonin on osteoclast functions
Shunyu Wang, Xiaoying YanResearch Article: Biomedical Research
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Experimental study on effect of calcitonin on osteoclast functions
Shunyu Wang, Xiaoying YanResearch Article: Biomedical Research
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Investigating the effect of performing the quiet time protocol on the sleep quality of cardiac patients
Milad Borji, Masoumeh Otaghi, Ebrahim Salimi, Parisa SaneiResearch Article: Biomedical Research
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Investigating the effect of performing the quiet time protocol on the sleep quality of cardiac patients
Milad Borji, Masoumeh Otaghi, Ebrahim Salimi, Parisa SaneiResearch Article: Biomedical Research
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Insomnia in patients with obstructive sleep apnea compared with controls
Hui Huang, Juan Xiong, Yanhong Hu, Jiafu Liu, Hao LiuResearch Article: Biomedical Research
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Insomnia in patients with obstructive sleep apnea compared with controls
Hui Huang, Juan Xiong, Yanhong Hu, Jiafu Liu, Hao LiuResearch Article: Biomedical Research
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Alternative markers of glycemic status in diabetes mellitus
Anupama Hegde, Ramya Shenoy?, Prajwal D?Mello, Smitha A, Tintu A, Poornima Manjrekar -
Alternative markers of glycemic status in diabetes mellitus
Anupama Hegde, Ramya Shenoy?, Prajwal D?Mello, Smitha A, Tintu A, Poornima Manjrekar
Conference Proceedings
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Obstetric services in low income countries (Sudan as an example)
Hayat Elfil -
Obstetric services in low income countries (Sudan as an example)
Hayat Elfil -
CURATIVE MEDICAL TREATMENT FOR ACUTE APPENDICITIS WITHOUT SURGICAL APPENDICECTOMY (JABER MANEUVER)
Diaa Eddin Mustafa Jaber and Mustafa JaberScientific Tracks Abstracts: Journal of Advanced Surgical Research
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CURATIVE MEDICAL TREATMENT FOR ACUTE APPENDICITIS WITHOUT SURGICAL APPENDICECTOMY (JABER MANEUVER)
Diaa Eddin Mustafa Jaber and Mustafa JaberScientific Tracks Abstracts: Journal of Advanced Surgical Research
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PREVALENCE OF OVERWEIGHT AND OBESITY AND ASSOCIATED RISK FACTORS AMONG SCHOOL CHILDREN IN JORDAN
Al Hourani HPosters & Accepted Abstracts: Biomedical Research
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PREVALENCE OF OVERWEIGHT AND OBESITY AND ASSOCIATED RISK FACTORS AMONG SCHOOL CHILDREN IN JORDAN
Al Hourani HPosters & Accepted Abstracts: Biomedical Research
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MOLECULES TARGETING CANCER STEM CELLS
Maithili A Athavale, Sandip Gavade and Sangeeta SrivastavaScientific Tracks Abstracts: Journal of Medical Oncology and Therapeutics
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MOLECULES TARGETING CANCER STEM CELLS
Maithili A Athavale, Sandip Gavade and Sangeeta SrivastavaScientific Tracks Abstracts: Journal of Medical Oncology and Therapeutics
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In silico, in vitro and in vivo studies for analyzing the propranolol action on cholinergic and carbonic anhydrase systems
Emily L Castillo-Garcia, Marvin A Soriano-Ursua, Fabiola J Cipres-Flores, Erik Andrade-Jorge and Eunice D Farfan-GarciaPosters & Accepted Abstracts: Journal of Pharmacology and Therapeutic Research
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In silico, in vitro and in vivo studies for analyzing the propranolol action on cholinergic and carbonic anhydrase systems
Emily L Castillo-Garcia, Marvin A Soriano-Ursua, Fabiola J Cipres-Flores, Erik Andrade-Jorge and Eunice D Farfan-GarciaPosters & Accepted Abstracts: Journal of Pharmacology and Therapeutic Research