TRANSITION METAL COMPLEXES/ORGANOMETALLIC COMPOUNDS AS ANTICANCER/ANTI-HIV DRUGS OR IN PHARMACEUTICAL INDUSTRY
Joint Event on International Conference on ADVANCED MATERIALS AND POLYMER SCIENCE & International Conference and Expo on SEPARATION TECHNIQUES
October 19-20, 2018 | Tokyo, Japan
Prakash MMS Kinthada
Sree Vidyanikethan Engineering College, India
Posters & Accepted Abstracts : Mater Sci Nanotechnol
Abstract:
Cancer is a dreadful disease and any practical solution in combating this disease is of paramount importance to public health. Cancer patients have burdened by drug induced toxic side effects, and no turned to seek help from the complementary and alternative medicine hoping for a better cure. Research on platinum-based drugs and non-platinum-based drugs is a Multi-Million Dollar Industry in USA and there is every need to produce safe drugs for the cure of this monstrous disease. Flavonoids have a long history of use in traditional medicines in many cultures. This talk would mainly encompass different transition metal complexes/ organometallic compounds that are presently used as drugs, especially anticancer and anti-HIV drugs, apart from anti-inflammatory, antimicrobial, antibacterial and diseases like arthritis and Parkinsonâs disease etc. This talk would mainly focus on the use of medicinal chemistry and its application to drug design and development in pharmaceutical industry, especially transition metal complexes and organometallic compounds viz. gold, platinum, palladium and ruthenium apart from copper, cobalt, iron, nickel, zinc, cadmium etc. The main emphasis of this talk would be on different class of ligands, their Schiffâs bases and transition metal complexes especially Au, Pt, Pd and Ru, with the main aim of designing, developing very novel small molecules, as possible and extremely potential candidates as anti-cancer and anti-HIV drugs. The talk would provide an overview of current programs being undertaken in our laboratories, especially focused on the development of potent ligands capable of recognizing binding sites and diverse strategies employed by my group for elucidation of anti-cancer and anti-HIV drug leads to circumvent the problem caused by cis-platin.
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