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The drug allergy app: Key strategy to overcome barriers to best practice
Joint Event on Global Experts Meeting on STD-AIDS and Infectious Diseases & 12th International Conference on Allergy, Immunology and Rheumatology
November 21-22, 2019 | Singapore
Shuayb E,G Calisti, A Amini, L Hernandez, L Owens,R Carman, K Dodgson, K Alexander and T Garcez
University NHS Foundation Trust-MFT, UK Birmingham City University, UK University of Manchester, UK
Posters & Accepted Abstracts : J Infectious Disease Med Microbiol
Abstract:
Drug allergies are common. They limit treatment options, can
lead to medication errors, suboptimal management and result
in increased morbidity, mortality, prolonged hospitalisation
and costs. Accurate collection and documentation of drug
allergy history is essential to minimise the risk of serious
medication errors.
Aim:
• To develop a drug allergy app that will guide drug
allergy history taking and documentation and serve
as an educational platform that encourages safe
medical practice and reinforce best practice.
•• The classification generated by the app is based on
the NICE clinical guidance [183] on the diagnosis and
management of drug allergies.
Objectives:
• To evaluate the accuracy of penicillin allergy history
documentation at the Trust and whether current
practice is in line with NICE clinical guidance 183.
•• To assess prescribers knowledge of penicillin allergy
diagnosis and management
• To Identify prescribers views on best practice
• To explore practical aspects of implementing a de-labelling
pathway in an NHS hospital Results and discussion:
We found that inappropriate penicillin allergy labelling
(In-PenA) is related to many factors, these included:
knowledge gaps, lack of training in allergy medicine amongst
healthcare professionals and errors in documentation. In-
PenA may subsequently increase the risk of multi-resistant
microorganisms such as Methicillin Resistant Staphylococcus
aureus (MRSA) and Clostridium difficile (C diff). The algorithm
has the lowest risk for misclassification of outcomes with a
high NPV (100%) and sensitivity (100%) with good PPV (95%)
and Specificity (96%) on the retrospective validation. It is
currently undergoing prospective validation with favourable
outcome.
Conclusion: The drug allergy App may revolutionise the
prescribers approach to patients with a penicillin allergy
label. From our survey of prescribers; there was an obvious
tendency to adopt an over-cautious approach to prescribing
alternative beta-lactams in patients with reported penicillin
allergy.
Biography:
E-mail: shuayb.elkhalifa@srft.nhs.uk
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