Repetitive Transcranial Magnetic Stimulation improves Depressive symptoms and quality of life of Poststroke patients - Prospective case series study
19th International Conference on Neurology and Neurological Disorders
November 04-05, 2019 | Melbourne, Australia
Hercilio Barbosa da Silva Junior
Neuronus Institute, Brazil
Posters & Accepted Abstracts : J Neurol Neurorehabil Res
Abstract:
Poststroke depression (PSD) is a serious psychiatric complication
often reported after a stroke. Nearly a third of stroke survivors
experience depressive symptoms at some point, affecting their
functional recovery and quality of life. In recent years, repetitive
transcranial magnetic stimulation (rTMS) has been studied by
many researchers and found to be a safe supporting tool for
the treatment of PSD.
Objective: We aim to evaluate the effects of rTMS on PSD and
on the quality of life of poststroke patients.
Method: A prospective clinical case series, performed at CRER
Rehabilitation, Brazil, between June 2016 and May 2017. A
nonprobabilistic sample (n=15) was divided into 2 groups
(excitatory stimulation in F3, n=8; inhibitory stimulation in
F4, n=7) and underwent 20 sessions of rTMS. Individuals
were assessed according to the 17-item Hamilton Depression
Rating Scale (HAM-D17) and World Health Organization
Quality of Life-Brief Version (WHOQOL-BREF) questionnaire
at 3 different moments: baseline, at the end of the treatment,
and in a 1-month follow-up meeting.
Results: Both groups presented a significant change in the
score of all WHOQOL-BREF domains and in HAM-D17. In
the group that received inhibitory stimulation (F4), score
changes were continuous and gradual, comparing the 3
moments. In the excitatory stimulated (F3) group, however,
the improvement in scores was more expressive between
baseline and the second moment, without significant changes
in the follow-up.
Conclusions: The findings of this clinical study suggest that
rTMS can be a promising tool, capable of relieving depressive
symptoms and helping in the improvement of poststroke
patients’ quality of life.
Biography:
Hercilio Barbosa da Silva Junior is a Psychologist (2004) and Neuropsychologist (2008) and he has a Master degree in Health Sciences from the Federal University of Goiás, Brazil (2017). He worked in a huge local rehabilitation center for almost 6 years (2011-2016), where he helped to implant the Neuromodulation Lab in 2013. Since then he research non-invasive brain stimulation techniques (rTMS and tDCS) in the treatment of neurological disorders (mood, memory and language recovery after stroke or traumatic brain injuries), psychiatric disorders (anxiety and mood disorders) and learning disorders (ADD and ADHD). He is the founder director of the Neuronus Institute for Trans-disciplinary Brain Studies located in Goiânia, Goiás, Brazil, where he is based.
E-mail: hercilio@neuronus.com.br
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