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Novelties comparison of regional vs. local arterial parameters using a new US Technology
10th International Conference on Neurological Disorders and Stroke
September 13, 2021 | Webinar
Pedro Jose Forcada
Cardio Arenales and DIM. Buenos Aires, Argentina
Scientific Tracks Abstracts : J Brain Neurol
Abstract:
Environment: It has been described that muscular arteries behaviour is different from aorta and regional parameters like IMT, atherosclerotic plaques burden, PWV-c and endothelial function are related with age and risk factors and are powerful prognostic markers but it is not the case of local parameters like wall shear stress (WSS), local PWV or beta index in muscular arteries like common carotid artery, only just recently available in the clinical practice. Objective: To analyze the relationship of regional and local arterial parameters with age and its potential use in the clinical practice. Methods: We evaluated 100 consecutive patients from april 2019 to february 2020 with a Resona 7 (Mindray) US device with tools to measure IMT, atherosclerotic load, PWV and endothelial function and by means of VFlow Doppler, an innovative multivectorial Doppler technology, we evaluated WSS and with radiofrequency edge detectors, stiffness parameters like PWV and beta index. Results: IMT remodelling, plaques burden, PWV correlated tightly with age and endothelial function did but inverserly (regression p >0.05). Local carotid parameters like wall shear stress, PWV and beta index were grouped whithin a range, independently of age. (regression p NS). Conclusion: The evaluation of local parameters has been proposed as markers of arterial disease and they are independent of age which makes it easier to detect abnormal values out of range, early markers of vascular disease, even before atherosclerosis is present. WSS is used for the first time in the current clinical practice.
Biography:
Pedro Jose Forcada is MD (1982) PhD (2016), cardiologist, specialist in Hypertension and Cardiovascular Mechanics. Associate Professor of Buenos Aires University and four other Universities. Member of the Argentinean Cardiology and Hypertension Societies. Member of Artery Research and the Panamerican College of Endothelium. Past President of Artery LATAM. Published more than 250 papers and communications, international speaker in 140 Meetings and wrote several chapters in Cardiovascular Prevention and Vascular Mechanics books. Currently is Head of the Vascular Laboratory in CardioArenales and DIM both institutions in Buenos Aires ARGENTINA.
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