Nickel-Coralline biomaterials for repair of brain damage
2nd International Conference on Biomaterials and Nanomaterials & Materials Physics and Materials Science
May 20-21, 2019 | Vienna, Austria
Danny Baranes
Ariel University, Israel
Keynote : Mater Sci Nanotechnol
Abstract:
Biomaterials can provide supportive microenvironment for cell growth and exciting opportunities for tissue regeneration. We found that biomaterials derived from the calcium carbonate skeleton of corals in the crystalline form of aragonite are protective and nurturing scaffolds for nervous tissue growth and survival in vitro. Moreover, implantation of coral skeleton into brain wounds generated following traumatic brain injury in mice causes tissue restoration and functional recovery. Implanted mice showed elevated level of glial fibrillary acidic protein and nestin, markers of nervous tissue generation, as well as reduced anxiety, elevated learning capacity and improved recovery from motor impairment, compared to injured but not implanted mice. These results place coralline scaffolds as a potential new mean to repair damage in the central nervous system.
Biography:
Danny Baranes has established his experience in neuroscience in the lab of the Nobel laureate Dr. Eric Kandel at Columbia University, New York and moved on to study tissue engineering of the central nervous system. He publishes in leading international scientific journals and conferences. He is associate professor and head of the department of molecular biology at Ariel University, Israel.
E-mail: dannyb@ariel.ac.il
PDF HTML