+44 1400 530055New data regarding the validation of the Pediatric Visceral Adipose Tissue Index (VAIP)
10th American Pediatrics healthcare & Pediatric Infectious Diseases Congress
September 20-22, 2017 | Toronto, Canada
Maria Jose Garces Hernandez
Universidad Nacional Autónoma de México, Mexico
Posters & Accepted Abstracts : Pediatric Healthcare & Pediatric Infections
Abstract:
Introduction: Visceral Adiposity Index (VAI) is a mathematical model associated with cardiometabolic diseases in adults. Previous studies in pediatric population have failed to demonstrate any association of VAI with metabolic and cardiovascular risk. In a previous paper we adapted VAI components to pediatric population (VAIP); the aim of the present study was to analyze the correlation of insulin resistance indexes and surrogate markers of cardiovascular abnormalities in order to validate VAIP. Methods: A prospective analysis was performed. A hundred children (normal weight, overweight and obese) between 8 and 12 years of age were recruited. Correlation analysis between risk variables (intima media thickness (IMT), flow mediated dilatation (FMD), HOMA-IR and MatsudaISI indexes, Visceral Fat Adiposity (VFA), Body Fat, and preperitoneal fat thickness (PP)) and VAIP was performed. Pearson and Spearman correlations were done. Cut points were designed using ROC curves and Odds ratios calculated by logistic regression analysis. Results: Significant strong correlation was found between VAIP and HOMA-IR (r=0.537, p=0.001), Matsuda (r=-0.607, p=0.001), IMT (r= 0.705, p=0.001), FMD (r = -0.464, p= 0.001), VFA (r= 0.616, p= 0.001), Body Fat (r= 0.735, p= 0.001), and PP (r= 0.696, p= 0.001). For children with obesity, the best cut off point of VAIP to predict insulin resistance was 4.88. All the children with obesity had abnormal values regarding IMT. Conclusions: Adjusted VAIP has a strong correlation with adiposity and correlates with cardiovascular and metabolic distress. It could be a helpful tool for identifying children at cardiometabolic risks, and for assessment of these children throughout intervention strategies.
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