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Evaluation of concentration and toxicity of Bisphenol A in food grade plastic and its degradation by bacteria

7th World Congress on Pharmacological and Toxicological Studies
December 14, 2022 | Webinar

Garima Kaushik

Central University of Rajasthan, India

Keynote : J Pharmacol Ther Res

Abstract:

Bisphenol A (BPA) is the man-made organic compound which is an important polymer used for the manufacturing of plasticizers, polycarbonates and epoxy resins. Plastic waste is increased in our environment due to its increasing demand day by day. Bisphenol A also known as an endocrine disruptor which mimics female sex hormone estrogen. Bisphenol A is acting as hormones so can induce cellular reactions and changes at very lower concentration. Thus determination of the concentration of BPA, its toxicity on soil environment and its degradation methods is of research interest. The developed method during this research project helps to determine the level of exposure and its toxicity and degradation methods. The 9 plastics items were analysed using UV/VIS spectrophotometer, all of them have significant amount of Bispehnol A present, the highest concentration of BPA was observed in Black polybags with 42.78 ppm followed by slice juice bottle (42.11 ppm) then baby bottle with 38.56 ppm. Here, we also investigated the toxicity of BPA on soil microflora by evaluating the CFU/ml. Adverse effect of BPA seen on microbial colonies number, the control plates CFU/ ml was observed TNTC (Too numerous to count) while as the BPA concentration of 250 ppm and 500 ppm applied to culture the significant reduction in growth is observed respectively, 9 x 106 CFU/ml in 250 ppm BPA treated plate and 1.2 x 106 CFU/ml in 500 ppm BPA treated plate. For the determination of Rhizobium activity, a clear zone of inhibition was observed around discs and wells poured with 500 ppm BPA. The significant impact of BPA was also seen on Phosphate solubilizing bacteria (PSB). The present study is being extrapolated to see the effect of bacterial treatment in degrading BPA in lab scale experiments and results were analysed through HPLC.
Recent Publications :
1. G. Kaushik, S. Kumar, & R. E. Masto Evaluation of the Fuel Value and Soil Application Potential of the Cadmium Contaminated Biochar Obtained after Water Treatment Springer Link journal Solid Fuel Chemistry volume 54, pages411–417 (2020)
2. Garima Kaushik, bedabratbarooah & Mohd A. Dar Biochemical effects of three personal care products on growth and development in Cicer arietinum (chickpea) and Vigna aconitifolia (moth bean) science direct Volume 18, June 2022, 101051
3. Garima Kaushik, Indu shekharthakur & kritikasharma Occurrence and distribution of pharmaceutical compounds and their environmental impacts: A review Science Direct Volume 16, December 2021, 100841

Biography:

Garima Kaushik is currently working as an assistant professor, in Department of Environmental Science, School of Earth Science, Central University of Rajasthan since 2011. She is a gold medallist in B. Sc. And M.Sc. From University of Rajasthan and obtained Ph.D. In the field of Environmental Biotechnology, from Jawaharlal Nehru University, New Delhi in 2009. She has also served as an Published several research papers in the field of bioremediation, climate change adaptation in international and national peer reviewed journals and has contributed to organizing various conferences and seminars. She has also participated in various academic events at national and international level and is also the life member of many academic societies including IWA and BRSI. She is a recipient of Dewang Mehta National Education award for Best Faculty for Environment Management in 2016. She has worked on national and international scientific projects including Indo Mexico International Project for 2017-2020.

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