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Controlled-Functionalization Of Silica Nanoparticles For Improving Isotopes Separation Of Thallium-201 And Lead-201
2nd International Conferences on Nanotechnology & Chemistry
April 06-07, 2022 | Webinar
Ibrahim Aljammaz
Research Center of King Faisal Specialist Hospital Saudi Arabia
Scientific Tracks Abstracts : J Pharm Chem Chem Sci
Abstract:
Many techniques have been applied for the separation of ion metals such as chemical precipitation, electro-flotation, ion exchange, reverse osmosis, and adsorption. However, adsorption is considered as an effective purification and separation technique. The most effective material are the nanomaterial based adsorbents that have been applied nowadays for ion metals separation. Nanostructure adsorbents have exhibited much higher efficiency and faster adsorption rates in water treatment when compared to traditional ones. The isolation of the lead-201 (Pb-201) from the stable thallium-203 (Tl-203) is prerequisite before the isolation of radioactive thallium-201 (Tl-201) from radioactive Pb-201. Therefore, functionalization of the silica-based nanoparticles with amino groups for improvement of the separation affinity towards isotopes of Pb was developed. The fabrication process was managed to allow the incorporation of ethylenediamine tetra acetic acid (EDTA) in the entire structure of the silica nanoparticles resulting in improved character for separation of Tl-201 from lead-201. The SEM and TEM examination for the prepared silica-EDTA particles showed a uniform sample shape, with porosity in case removing surfactant. The FTIR analysis confirms the presence nitrogen containing compound and hydroxyl groups in the surface of the prepared silica particles. The effect of the pH on the separation of lead and thallium was investigated in the range between pH 2 to 7. The results revealed that the pH 3 was the most suitable for adsorption and efficient separation. The adsorption process for separation was studied and characterized in term of kinetic and isotherm. The adsorption process was found to follow the second order kinetic model and more fitted with Freundlich isotherm assumptions. This optimized new method appeared to be promising for utilization in the manufacturing of 201thallium chloride (201TlCl3) radiopharmaceutical that is routinely used in nuclear medicine for the diagnostic of heart disease.
Biography:
Ibrahim Aljammaz is from Cyclotron and Radiopharmaceuticals Department, Research Center of King Faisal Specialist Hospital Saudi Arabia. His research interests are Nanochemistry. He also attended many international conferences.
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