Cervical spine and cord angle mismatch in the pathogenesis of myelopathy
Joint Event on 3rd International Conference on Spine and Spine Disorders & International Conference on Addiction Research and Therapy
November 26-27, 2018 | Dubai, UAE
Tomasz Tykocki and Guy Wynne-Jones
Royal Victoria Infirmary Newcastle upon Tyne Hospital, UK
Posters & Accepted Abstracts : J Neurol Neurorehabil Res
Abstract:
Background: Cervical Myelopathy is a complex pathology and
dynamic compression of the tethered cervical cord, which may
be responsible for clinical symptoms.
Methods: Patients with Cervical Canal Stenosis who had
magnetic resonance imaging in flexion and extension positions
were retrospectively reviewed. All cases were evaluated in
Nurick grade. The cervical parameters-Cervical Cord (CC)
angle, Cervical Lordosis, and Spine/Cord (S/C) angle ratio-were
measured on the magnetic resonance imaging. Mean values of
these parameters were compared between non-myelopathic
(Nurick grade 0) and myelopathic groups (Nurick grades 1-5).
A multinomial ordinal logistic regression was used to predict
outcome for Nurick grade using the CC angle, the cervical
lordosis angle, and the S/C angle ratio as independent variables.
Results: A total of 65 patients (35 men) with the mean age of 58.6
± 11.4 years were analyzed. A comparison of means between
Nurick grade 0 against each of myelopathic grades 1-5 revealed
significant differences only for the S/C angle ratio. A cumulative
comparison between non-myelopathic and myelopathic grades
for the S/C angle ratio showed significant difference of 0.29
(1.16 ± 0.5 vs. 1.45 ± 0.6, respectively; P < 0.05). Cumulative
comparison for the CC angle difference in flexion and extension
lordosis did not show substantial differences. The S/C angle
ratio was the only significant parameter in the prediction of
the Nurick grade with an odds ratio of 2.63 (95% confidence
interval 2.11-2.79).
Conclusions: A positive correlation between Nurick grade and
cervical spine and cord angle mismatch was found.
Biography:
E-mail:
ttykocki@gmail.comPDF HTML