Celiac disease: Diagnostic dilemma
2nd World Congress on Pediatrics and Clinical Pediatrics
June 12-13, 2019 | Edinburgh, Scotland
Bharat Parmar
Zydus Medical College, India
Scientific Tracks Abstracts : Curr Pediatr Res
Abstract:
Celiac disease, an autoimmune disorders, occurs in genetically susceptible individuals and is triggered by the ingestion of a well-idenfined autoantigen- gluten. It affects primarily the small intestine,where it progressively leads to flattening of small intestinal mucosa. Three cereals contain gluten and are toxic for Celiac patients – wheat,rye and barley. It occurs more commonly in relatives of celiac patients and some at risk groups. It causes gastrointestinal symtoms, predominantly chronic diarrhoea with wastings, but also many extra-intestinal menifestations can be present alone. Suspected patient should be screened with transglutaminase + total serum IgA and if positive, confirmed by biopsy before the gluten-free diet is started. A gluten free diet typically reverses all signs and symptoms within a short time. Monitoring of the patient to verify ongoing dietetic compliance is fundamental in order to ensure that all possible complications, including malignancies, are avoided.
Biography:
Bharat Parmar has completed M.D (Paediatrics) From Gujarat University Ahmedabad Gujarat India. He is working as a Professor and Head of Paediatrics Department at ZYDUS Medical college Civil hospital. He has completed 25 teaching experience in B.J Medical College Ahmedabad, Gujarat India. He has published 15 research paper in national and international journal. Recently one publication cited in Science Direct and Pub Med. He has been serving as an editorial board member of reputed Journal.
E-mail: bjpdr@hotmail.com
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