Association between Onodera’s prognostic nutrition index and infection-related hospitalizations in patients with schizophrenia
17th International Conference on Clinical Nutrition and Fitness
November 21-22, 2019 | Singapore
Bo-Jian Wu
Yuli Hospital, Taiwan
Posters & Accepted Abstracts : J Nutr Hum Health
Abstract:
Background: Protein-energy wasting is associated with poor
outcome in various clinical settings. However, the prevalence of
moderate malnutrition and the prognostic impact of nutritional
status are rarely explored in hospitalized patients with
schizophrenia. This study aimed to assess the prevalence of
moderate malnutrition and the predictive ability of Onodera’s
prognostic nutrition index (OPNI) on occurrence of infectionrelated
hospitalizations for hospitalized schizophrenia patients.
Methods: All measurements, including nutritional assessment
were performed among hospitalized 582 patients with chronic
schizophrenia (64.8% man, mean age 53.8 ±9.6 years). The
mean follows up period was 408 days. Cox regression models
adjusting for age, sex and Charlson comorbidity index, were
used to explore the association between OPNI and infectionrelated
hospitalizations.
Results: At the end of the study, 42 patients had infectionrelated
hospitalizations. The prevalence of moderate
malnutrition defined by OPNI scores lower than 45 was 15.8%
(92/582). Moderate malnutrition expressed a significant
association with falls in this study. The adjusted hazard
ratios (95% confidence intervals) of moderate malnutrition
were 2.42 (1.17–4.59) for infection-related hospitalizations.
Conclusions: OPNI is a useful tool for identifying chronic
schizophrenic patients at risk of moderate malnutrition
and infection-related hospitalizations. Further studies are
needed to explore whether early detection of patients
with schizophrenia at risk for malnutrition could reduce
the morbidity and mortality by appropriate interventions
Biography:
Bo-Jian Wu has completed his MD from National Défense Medical Center in Taiwan. He has completed his MSc from the Institute of Epidemiology of National Taiwan University and Ph.D. from the institute of Clinical Medicine of National Yangming University. Now he is certified psychiatrist, and an attending physician of Department of Psychiatry, Yuli Hospital, Ministry of Health and Welfare, Hualien, Taiwan. His research mainly focus on schizophrenia, and have over 30 publications.
E-mail: woobojian@gmail.com
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