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Opinion Article - Journal of Biomedical Imaging and Bioengineering (2023) Volume 7, Issue 3
Visualizing the unseen and advances in biological imaging techniques.
Rahali Rees *
Department of Biomedical Engineering, Swansea University, Swansea, United Kingdom
- *Corresponding Author:
- Rahali Rees
Department of Biomedical Engineering,
Swansea University,
Swansea, United Kingdom
E-mail: Rahali.r@swansea.ac.uk
Received: 23-May-2023, Manuscript No. AABIB-23-97336; Editor assigned: 05-Jun-2023, PreQC No. AABIB-23-97336 (PQ); Reviewed: 19-Jun-2023, QC No. AABIB-23-97336; Revised: 23-Jun-2023, Manuscript No. AABIB-23-97336; Published: 23-Jun-2023, DOI:10.35841/aabib-7.3.185
Citation: Rees R, Visualizing the unseen and advances in biological imaging techniques. J Biomed Imag Bioeng. 2023;7(3):185.
Introduction
The ability to visualize the unseen has been a long-standing goal of scientists and researchers in various fields. In the realm of biology, this pursuit has been aided by a range of technological advancements in imaging techniques. Over the past few decades, there have been remarkable breakthroughs in biological imaging, with new techniques being developed that allow scientists to see the inner workings of cells and organisms at increasingly high resolutions. One of the most significant advances in biological imaging has been the development of confocal microscopy. This technique allows scientists to generate detailed images of living cells and tissues by using laser beams to focus on specific areas of interest [1].
Confocal microscopy offers a range of advantages over traditional microscopy, including higher resolution, improved contrast, and reduced background noise. This technique has enabled researchers to observe cellular processes in real-time, making it a valuable tool for studying cellular dynamics. Another notable advance in biological imaging has been the development of super-resolution microscopy. This technique uses specialized fluorescent molecules and advanced optical systems to achieve resolutions beyond the limits of traditional microscopy. Super-resolution microscopy has allowed researchers to study the intricate structures of cells and tissues in unprecedented detail. For example, it has enabled scientists to visualize the complex networks of proteins that make up the cytoskeleton, as well as the interactions between molecules that control cellular signaling pathways [2].
In addition to microscopy techniques, there have been advances in other forms of biological imaging, such as Magnetic Resonance Imaging (MRI) and Computed Tomography (CT) scanning. These techniques have traditionally been used in medical diagnostics, but they are increasingly being applied in biological research to study living organisms and tissues. MRI, for example, has been used to visualize the activity of neurons in the brain and to study the effects of disease on tissue structure and function. The ability to visualize biological structures and processes has also led to advances in the field of medical research and healthcare. For example, imaging techniques such as MRI and CT scanning are now widely used in clinical settings to diagnose and monitor a range of medical conditions. These techniques have enabled doctors to detect and diagnose diseases at earlier stages, leading to better treatment outcomes and improved patient care [3].
In addition, advances in biological imaging have also led to the development of new drugs and therapies. By visualizing the molecular interactions between drugs and target proteins, scientists are able to design more effective drugs that specifically target disease-causing molecules while minimizing side effects. For example, advances in super-resolution microscopy have allowed researchers to study the interactions between drugs and proteins at a level of detail that was previously impossible. The development of new imaging techniques has also been driven by the need to better understand the impact of environmental factors on biological systems. For example, climate change and pollution can have significant effects on the behavior and health of organisms. By using imaging techniques to study the effects of these factors on cellular and organismal processes, researchers are able to better understand how to mitigate the negative impacts of environmental stressors [4].
In addition, advances in biological imaging have also led to the development of new drugs and therapies. By visualizing the molecular interactions between drugs and target proteins, scientists are able to design more effective drugs that specifically target disease-causing molecules while minimizing side effects. For example, advances in super-resolution microscopy have allowed researchers to study the interactions between drugs and proteins at a level of detail that was previously impossible. The development of new imaging techniques has also been driven by the need to better understand the impact of environmental factors on biological systems. For example, climate change and pollution can have significant effects on the behavior and health of organisms. By using imaging techniques to study the effects of these factors on cellular and organismal processes, researchers are able to better understand how to mitigate the negative impacts of environmental stressors [5].
References
- Liew C. The future of radiology augmented with artificial intelligence: A strategy for success. Eur J Radiol. 2018;102:152-6.
- Hosny A, Parmar C, Quackenbush J, et al. Artificial intelligence in radiology. Nat Rev Cancer. 2018;18(8):500-10.
- Rezazade Mehrizi MH, Van Ooijen P, Homan M. Applications of Artificial Intelligence (AI) in diagnostic radiology: A technography study. Eur Radiol. 2021;31:1805-11.
- Eliceiri KW, Berthold MR, Goldberg IG, et al. Biological imaging software tools. Nature methods. 2012;9(7):697-710.
- Sekar RB, Periasamy A. Fluorescence Resonance Energy Transfer (FRET) microscopy imaging of live cell protein localizations. J Cell Biol. 2003;160(5):629.