Perspective - Archives of General Internal Medicine (2023) Volume 7, Issue 3

Untangling the Mysteries: The Polycystic Ovary Syndrome (PCOS) Journey.

Zohl Dahlgren ^*

Department of Obstetrics and Gynecology, Sahlgrenska University Hospital, Boston, USA

*Corresponding Author:

Zohl Dahlgren
Department of Obstetrics and Gynecology
Sahlgrenska University Hospital
Boston, USA
E-mail: zohl.dahl5@gu.se

Received:27 May-2023, Manuscript No. AAAGIM-23-103435; Editor assigned:01-Jun-2023, PreQC No. AAAGIM-23-103435 (PQ); Reviewed:16-Jun-2023, QC No. AAAGIM-23-103435; Revised:19-Jun-2023, Manuscript No. AAAGIM-23-103435 (R); Published:28-Jun-2023, DOI:10.35841/ aaaa-7.3.180

Citation: Dahlgren Z. Managing Post-Traumatic Stress Disorder (PTSD) from trauma to healing. Arch Gen Intern Med. 2023;7(3):180

Abstract

"Untangling the Mysteries: The Polycystic Ovary Syndrome (PCOS) Journey" delves into the multifaceted nature of Polycystic Ovary Syndrome (PCOS) and the obstacles that people with this ailment experience. This detailed abstract summarises the main points discussed in the paper. The study looks into the diagnostic criteria, including clinical and biochemical indicators used to identify PCOS. The abstract closes by emphasising the significance of on-going study and progress in understanding PCOS. It emphasises the importance of improved knowledge, education, and support networks for people with PCOS, with a focus on empowering them to navigate their own paths and properly manage the complexity of this syndrome.

Abstract

"Untangling the Mysteries: The Polycystic Ovary Syndrome (PCOS) Journey" delves into the multifaceted nature of Polycystic Ovary Syndrome (PCOS) and the obstacles that people with this ailment experience. This detailed abstract summarises the main points discussed in the paper. The study looks into the diagnostic criteria, including clinical and biochemical indicators used to identify PCOS. The abstract closes by emphasising the significance of on-going study and progress in understanding PCOS. It emphasises the importance of improved knowledge, education, and support networks for people with PCOS, with a focus on empowering them to navigate their own paths and properly manage the complexity of this syndrome.

Key words

Polycystic Ovary Syndrome (PCOS), Ovarian cysts, Menstruation, Hyperandrogenemia, Folliculogenesis, Hirsutism.

Introduction

Polycystic Ovary Syndrome (PCOS) affects a large number of women globally, causing a variety of complex symptoms that have an influence on their physical, mental, and reproductive health. The purpose of this abstract is to provide light on the complex interplay of hormonal imbalances, metabolic abnormalities, and genetic variables that contribute to the development and progression of PCOS. It explains the wide range of symptoms that people with PCOS encounter, such as irregular menstruation periods, ovarian cysts, and hirsutism. The impact of PCOS on fertility, mental health, and quality of life is also discussed, emphasising the significant emotional and psychological challenges that persons suffering from this disorder experience [1].

Furthermore, the abstract investigates the numerous therapy options for PCOS management. It covers lifestyle adjustments like diet and exercise, as well as pharmaceutical therapies including oral contraceptives, anti-androgens, and insulin sensitizers. The possible importance of assisted reproductive technology and surgical treatments is also discussed, emphasising the need for a personalised approach for each people based on their own requirements and goals [2].

The precise causes are unknown at this time; however androgen levels that are greater than usual play a role. Excess weight and family history, both of which are linked to insulin resistance, can also play a role. PCOS runs in families, implying a hereditary predisposition. The mechanism of inheritance is unknown. Some researchers proposed autosomal dominant inheritance connected to a single genetic flaw, but the majority of authors characterise PCOS as a polygenic condition [3].

A link has also been discovered between "pro-inflammatory" genotypes and PCOS. Environmental variables have a vital role in PCOS. Although PCOS appears to be more common among Asian and Middle Eastern women, other observations show the presence of several environmental factors, such as food, physical activity, and overall lifestyle. Folliculogenesis is influenced by a variety of variables. FSH deficiency (Follicle Stimulating Hormone), increased LH (Luteinizing Hormone), hyperandrogenemia, and insulin resistance are all symptoms of insulin resistance. Follicular fluid contributes to the development of PCOS. Vitamin D has been linked to the aetiology of PCOS. Vitamin D deficiency has been observed in obese PCOS individuals. Hypovitaminosis D may contribute to insulin resistance and reduced glucose tolerance. Gonadotropin-releasing hormone (GnRH), LH, and FSH are all involved in the pathophysiology of PCOS. Excessive LH secretion, which may be influenced by the frequency or amplitude of the GnRH impulse, can lead to aberrant folliculogenesis. Excess LH can cause early luteinization of primordial follicles and subsequent degeneration. LH may also trigger premature meiotic processes that degrade oocyte quality and lead to the development of embryonic aneuploidies [4].

It is beneficial to include healthful and enjoyable options in your diet when controlling PCOS. Here are some Mediterranean diets foods that can help you maintain a healthy weight and control PCOS symptoms includes:

•

Bake or broil omega-3-rich fish, such as salmon.

•

Olive oil can be used for butter or margarine.

•

Instead of meat, choose protein-rich legumes like beans.

•

Leafy greens (spinach, kale, lettuce, etc.), tomatoes, mushrooms, peppers, broccoli, cauliflower, snow peas, celery, and fennel are all good additions to your meals.

•

Choose whole grains such as brown rice, barley, and sorghum. Whole-grain breads and pastas can help keep blood sugar levels stable.

•

As a dessert alternative, try entire fruits. Whole fruits include fibre, which aids in satiety, digestion, and weight loss [5].

Conclusion

Comprehensive care for women with PCOS should include mental, emotional, cognitive, and social aspects of quality of life. To summarise, the pathophysiology of PCOS is not well known. PCOS is a systemic disease that begins early in intrauterine life rather than a reproductive pathology. There has been significant progress in the diagnosis and prevention of PCOS, including hormonal contraception, antiandrogen medications, metformin, and inositols. Insulin resistance and hyperinsulinemia are as serious as obesity and hirsutism. This condition may be better understood if more research is conducted in this area.

References

1. Goodarzi MO, Dumesic DA, Chazenbalk G, et al. Polycystic ovary syndrome: etiology, pathogenesis and diagnosis. . Nat Rev Endocrinol. 2011;7(4):219-31.

Indexed at, Google Scholar,Cross Ref

2. McKenna TJ. Pathogenesis and treatment of polycystic ovary syndrome.. N Engl J Med. 1988;318(9):558-62.

Indexed at, Google Scholar,Cross Ref

3. Legro RS, Arslanian SA, Ehrmann DA, et al. Diagnosis and treatment of polycystic ovary syndrome: an Endocrine Society clinical practice guideline.

Indexed at, Google Scholar, Cross Ref

4. Alnakash AH, Al-Tae e NK. Polycystic ovarian syndrome: the correlation between the LH/FSH ratio and disease manifestations.. Middle East Fertil. Soc. J.. 2007;12(1):35.

Google Scholar

5. Esmaeilzadeh S, Andarieh MG, Ghadimi R, et al. Body mass index and gonadotropin hormones (LH & FSH) associate with clinical symptoms among women with polycystic ovary syndrome. Glob J Health Sci. 2015;7(2):101.

Indexed at, Google Scholar, Cross Ref