Rapid Communication - Research in Clinical Dermatology (2021) Volume 4, Issue 2
Topical treatment for seborrheic keratoses could be a good alternative to surgery
Haque Khatun*Department of Plastic Surgery, East West University, Dhaka, Bangladesh
- *Corresponding Author:
- Haque Khatun
Department of Plastic Surgery
East West University
Dhaka, Bangladesh
E-mail: Khatun @haq.ac.bd
Accepted date: November 06, 2021
A skin corrective cream with urea and hydroxyl acids shows adequacy and decency in the treatment of patients with seborrheic keratoses, examiners revealed in a review distributed in the Diary of Restorative Dermatology. The observational review was directed at the dermatologic unit of a college clinic in Italy, selecting 20 patients (12 men) with seborrheic keratoses restricted in various body regions. Incorporation rules were age 18 years old or more established and a clinical determination of seborrheic keratoses. The total plan of the cream tried was made out of urea (42%), lactic corrosive (6%), mandelic corrosive (5%), salicylic corrosive (2%), thuja (0.2%), beta-glucan, allantoin, hyaluronic corrosive, marine collagen, and alphabisabolol [1].
Members put on the corrective gadget twice every day for 30 days, and clinical evaluations of their skin condition were recorded at standard and on day 30. The Regular routine Quality Record (DLQI) and epiluminescence microscopy were utilized to assess changes in the patients' personal satisfaction previously, then after the fact treatment. The essential endpoint was the corrective adequacy of the gadget, estimating the level of clinical vanishing of seborrheic keratoses and the progressions in dermatoscopic highlights pre-and post-treatment [2].
The patients had a critical decrease in the quantity of seborrheic keratoses and thickness after treatment. Their worldwide DLQI improved by 99.95% in 30 days. The DLQI expanded by 99.99% in men and by 99.92% in ladies, the review creators noted. Following 30 days, the decency of the treatment was thought of "superb" as indicated by 95% of members and "great" as per 5%. No perilesional skin changes were brought about by neighbourhood treatment, and the patients had no provocative reaction or hypopigmentation. In 2 patients, nearby erythema was seen in the space of the treated seborrheic keratoses inferable from mechanical injury. No antagonistic occasions were accounted for during treatment, and all members finished the review. "The most outstanding benefit of this gadget is that it very well may be self-applied by the patients at home," the specialists remarked. "The announced information propose that this restorative gadget is viable, safe, and all around endured in the treatment of seborrheic keratoses, because of the synergistic activity of its mixtures, which diminish nearby aggravation, tingling, and hyperkeratosis while further developing skin hydration" [3].
The treatment may likewise be gainful for other restricted types of hyperkeratotic skin injuries, including palmoplantar keratoderma and thick psoriatic plaques, as per the scientists. A seborrheic keratosis is an abnormal development of the skin. Although they are unattractive, the growths are not hazardous. However, a seborrheic keratosis can be difficult to distinguish from melanoma, a particularly dangerous type of skin cancer, in some situations. You should always have your skin checked by a doctor if it changes abruptly. Although a seborrheic keratosis isn't harmful, you shouldn't disregard any skin growths. It might be difficult to tell the difference between benign and hazardous growths. It's possible that what appears to be seborrheic keratosis is actually melanoma. A dermatologist can typically diagnose seborrheic keratosis just by looking at it. If there's any doubt, they'll likely remove some or all of the growth for laboratory testing. A skin biopsy is the medical term for this procedure. A qualified pathologist will analyse the biopsy under a microscope. This can aid your doctor in determining if the growth is seborrheic keratosis or malignancy (such as malignant melanoma) [4,5].
References
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- Herron MD, Bowen AR, Krueger GG. Seborrheic keratoses: a study comparing the standard cryosurgery with topical calcipotriene, topical tazarotene, and topical imiquimod. Int J Dermatol. 2004; 43:300-2.
- Wood LD, Stucki JK, Hollenbeak CS, et al. Effectiveness of cryosurgery vs curettage in the treatment of seborrheic keratoses. JAMA Dermatol. 2013;149:108-9.
- Hafner C, Vogt T. Seborrheic keratosis. JDDG: J Dtsch Dermatol Ges. 2008;6:664-77.