Journal of Cancer Immunology & Therapy

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.
Reach Us +1 (202) 780-3397

Short Communication - Journal of Cancer Immunology & Therapy (2024) Volume 7, Issue 3

The role of radiation therapy in modern oncology: Benefits and advancements.

Jeffrey Kidan *

Department of Radiation Oncology & Molecular Radiation Sciences, Johns Hopkins University School of Medicine, USA

*Corresponding Author:
Jeffrey Kidan
Department of Radiation Oncology & Molecular Radiation Sciences, Johns Hopkins University School of Medicine, USA
E-mail: Jkidan38@jhmi.edu

Received: 03-Jun -2024, Manuscript No. AAJCIT-24-138049; Editor assigned: 04-Jun-2024, PreQC No. AAJCIT-24-138049 (PQ); Reviewed:18-Jun-2024, QC No. AAJCIT-24-138049; Revised:24-Jun-2024, Manuscript No. AAJCIT-24-138049 (R); Published:01-Jul-2024, DOI:10.35841/aara-7.3.212

Citation: Kidan J., The role of radiation therapy in modern oncology: Benefits and advancements. J Cancer Immunol Ther. 2024;7(3):212

Visit for more related articles at Journal of Cancer Immunology & Therapy

Introduction

In the multifaceted battle against cancer, radiation therapy stands as a stalwart ally. Its role in modern oncology is indispensable, offering both curative and palliative benefits to patients. Over the years, radiation therapy has undergone significant advancements, making it more precise, effective, and tolerable. In this article, we delve into the benefits and recent advancements in radiation therapy, highlighting its pivotal role in the contemporary fight against cancer [1].

Unlike surgery, which physically removes tumors, radiation therapy is non-invasive and can be directed precisely to the tumor site, sparing surrounding healthy tissue. This precision is crucial in minimizing side effects and optimizing treatment outcomes [2].

Radiation therapy can be employed with curative intent, either as the primary treatment modality or in combination with surgery and chemotherapy. It is particularly effective in treating localized cancers, such as those in the breast, prostate, lung, and head and neck regions. By eradicating cancer cells, radiation therapy offers the possibility of long-term remission and even cure [3].

In cases where cancer has spread or is deemed inoperable, radiation therapy provides valuable palliative care. It can alleviate symptoms such as pain, bleeding, and obstruction, improving the patient's quality of life. Palliative radiation therapy aims to shrink tumors or relieve pressure on surrounding organs, offering comfort and relief to patients facing advanced stages of cancer [4].

For certain types of cancer, such as early-stage laryngeal or cervical cancer, radiation therapy enables organ preservation. By effectively treating the tumor without resorting to surgical removal, patients can retain essential functions and avoid the potential complications of surgery [5].

IGRT integrates advanced imaging techniques, such as CT scans or MRI, with radiation therapy delivery systems. This real-time imaging allows for precise localization and tracking of the tumor during treatment, ensuring accurate delivery of radiation while minimizing exposure to healthy tissues. IGRT is particularly beneficial for tumors located near critical structures or those prone to movement, such as lung or prostate tumors [6].

This technique utilizes computer-controlled linear accelerators to adjust the intensity and shape of radiation beams, sculpting them to match the contours of the tumor. IMRT reduces the risk of side effects and enables higher doses of radiation to be delivered safely, improving treatment outcomes [7].

These techniques are highly effective for treating tumors in the brain, spine, lung, liver, and other sites. By delivering high doses of radiation with submillimeter accuracy, SBRT and SRS achieve excellent tumor control while minimizing damage to surrounding tissues [8].

Radiation therapy, also known as radiotherapy, utilizes high-energy radiation to target and destroy cancer cells. It works by damaging the DNA within these cells, preventing them from multiplying and spreading [9].

IMRT delivers highly conformal doses of radiation to the tumor while sparing nearby healthy tissues. SBRT and SRS deliver precisely targeted radiation to small tumors or metastatic lesions in a limited number of treatment sessions [10].

conclusion

Radiation therapy continues to play a crucial role in modern oncology, offering both curative and palliative benefits to cancer patients. With advancements such as IGRT, IMRT, SBRT, and SRS, radiation therapy has become more precise, effective, and tolerable than ever before. By harnessing the power of radiation to target and destroy cancer cells while sparing healthy tissues, radiation therapy holds promise in improving treatment outcomes and enhancing the quality of life for cancer patients worldwide.

References

  1. Bucci MK, Bevan A, Roach III M. Advances in radiation therapy: conventional to 3D, to IMRT, to 4D, and beyond. CA Cancer J Clin. 2005;55(2):117-34.
  2. Google Scholar

  3. Baskar R, Lee KA, Yeo R, Yeoh KW. Cancer and radiation therapy: current advances and future directions. Int J Med Sci. 2012;9(3):193.
  4. Indexed at, Google Scholar, Cross Ref

  5. Xing L, Thorndyke B, Schreibmann E, Yang Y, Li TF, Kim GY, Luxton G, Koong A. Overview of image-guided radiation therapy. Med Dosimet. 2006;31(2):91-112.
  6. Indexed at, Google Scholar, Cross Ref

  7. Bortfeld T, Jeraj R. The physical basis and future of radiation therapy. Br J Radiol. 2011;84(1002):485-98.
  8. Indexed at, Google Scholar, Cross Ref

  9. Brahme A. Development of radiation therapy optimization. Acta Oncol. 2000;39(5):579-95.
  10. Indexed at, Google Scholar

  11. Borek C. Antioxidants and radiation therapy. J Nutrit. 2004;134(11):3207S-9S.
  12. Indexed at, Google Scholar

  13. Demaria S, Golden EB, Formenti SC. Role of local radiation therapy in cancer immunotherapy. JAMA Oncol. 2015;1(9):1325-32.
  14. Google Scholar

  15. Dawson LA, Jaffray DA. Advances in image-guided radiation therapy. Clin Oncol. 2007;25(8):938-46.
  16. Google Scholar

  17. Rutqvist LE, Rose C, Cavallin-Ståhl E. A systematic overview of radiation therapy effects in breast cancer. Acta Oncol. 2003;42(5-6):532-45.
  18. Google Scholar

  19. Whelan TJ, Pignol JP, Levine MN, Julian JA, MacKenzie R, Parpia S, Shelley W, Grimard L, Bowen J, Lukka H, Perera F. Long-term results of hypofractionated radiation therapy for breast cancer. N Eng J Med. 2010;362(6):513-20.
  20. Indexed at, Google Scholar

Get the App