Research and Reports on Genetics

All submissions of the EM system will be redirected to Online Manuscript Submission System. Authors are requested to submit articles directly to Online Manuscript Submission System of respective journal.
Reach Us +1 (202) 780-3397

Opinion Article - Research and Reports on Genetics (2024) Volume 6, Issue 3

The Intricacies of Recessive Traits: A Journey into Genetics

Francine Kershaw*

Department of Science, Queensland University, US

*Corresponding Author:
Francine Kershaw
Department of Science,
Queensland University,
US
E-mail:fkershawnr@dc.org

Received:21-Feb-2024,Manuscript No. AARRGS-24-129246; Editor assigned:24-Feb-2024,PreQC No. AARRGS-24-129246(PQ); Reviewed:09-Mar-2024,QC No. AARRGS-24-129246; Revised:13-Mar-2024, Manuscript No. AARRGS-24-129246 (R); Published:20-Mar-2024,DOI:10.35841/aarrgs-6.2.191

Citation: Kershaw F. The intricacies of recessive traits: A Journey into genetics.J Res Rep Genet.2024;6(3):201

Visit for more related articles at Research and Reports on Genetics

Introduction

In the vast tapestry of human genetics lies a phenomenon known as recessive traits, quietly shaping our physical attributes and predispositions. While dominant traits often take the spotlight, recessive traits play an equally significant role in defining who we are. Delving into the realms of molecular biology, we uncover the intricate mechanisms underlying recessive traits and their profound implications on heredity and human diversity. Recessive traits are genetic characteristics that manifest only when an individual inherits two copies of the recessive allele, one from each parent. Unlike dominant traits, which can overpower their recessive counterparts, recessive traits require a double dose to become phenotypically apparent. This inherent nature often conceals recessive traits within populations, making them less conspicuous but no less influential.[1,2].

The foundational principles of recessive traits trace back to Gregor Mendel’s experiments with pea plants in the 19th century. Through meticulous crossbreeding experiments, Mendel elucidated the laws of inheritance, unraveling the mechanisms governing the transmission of traits from one generation to the next. His work laid the groundwork for our understanding of recessive traits and their inheritance patterns.At the molecular level, recessive traits result from the presence of two recessive alleles of a gene. Alleles are different forms of a gene, and each individual inherits two alleles one from each parent—for every gene. In the case of recessive traits, individuals may carry one dominant allele and one recessive allele, remaining phenotypically dominant while harboring the recessive trait in their genetic makeup.[3,4].

The expression of recessive traits hinges on the interplay between dominant and recessive alleles. In heterozygous individuals those carrying both dominant and recessive alleles—the dominant allele typically masks the expression of the recessive trait. Only when an individual inherits two recessive alleles making them homozygous for the recessive trait does the recessive phenotype manifest.[5,6].

 

Numerous traits in humans exhibit recessive inheritance patterns, ranging from physical characteristics to genetic disorders. One well-known example is blue eye color, which often requires both parents to carry the recessive allele for its expression. Similarly, traits such as attached earlobes, straight hairline, and hitchhiker's thumb follow recessive inheritance patterns. While some recessive traits are benign or even aesthetically appealing, others carry significant implications for health. Recessive genetic disorders, such as cystic fibrosis, sickle cell anemia, and Tay-Sachs disease, result from inheriting two copies of a mutated recessive allele. These disorders underscore the importance of genetic counseling and screening to assess the risk of hereditary conditions and inform reproductive decisions 7,8].

 

 

The prevalence of recessive traits within populations reflects a complex interplay of genetic diversity, migration, and natural selection. In small, isolated populations, recessive traits may become more prevalent due to genetic drift and limited gene flow. Conversely, in larger populations with greater genetic diversity, recessive traits may remain rare or less pronounced.[9,10].

 

Conclusion

 

Recessive traits constitute an integral aspect of human genetics, influencing our physical attributes, health outcomes, and evolutionary trajectories. From Mendel’s pea plants to modern genomic studies, our understanding of recessive traits has deepened, shedding light on the intricacies of heredity and diversity. As we continue to unravel the mysteries of genetics, the significance of recessive traits in shaping who we are becomes increasingly apparent, reminding us of the remarkable complexity encoded within our DNA.

 

References

  1. Musante L, Ropers HH. Genetics of recessive cognitive disorders. Trends in Genetics. 2014;30(1):32-9.
  2. Indexed at, Google Scholar, Cross Ref

  3. Bonifati V. Autosomal recessive parkinsonism. 2012 ;18:S4-6.
  4. Google Scholar

  5. Truniger V, Aranda MA. Recessive resistance to plant viruses. Adv Vir Res. 2009;75:119-231.
  6. Indexed at, Google Scholar, Cross Ref

  7. Robertson A. The effect of inbreeding on the variation due to recessive genes. Gen.1952;37(2):189.
  8. Indexed at, Google Scholar

  9. Pereira-Smith OM, Smith JR. Evidence for the recessive nature of cellular immortality. Sci.1983 ;221(4614):964-6.
  10. Indexed at, Google Scholar, Cross Ref

  11. Heim WG. What is a recessive allele?. Amer Bio. 1991;53(2):94-7.
  12. Indexed at, Google Scholar, Cross Ref

  13. Lander ES, Botstein D. Homozygosity mapping: a way to map human recessive traits with the DNA of inbred children. Science. 1987;236(4808):1567-70.
  14. Indexed at, Google Scholar, Cross Ref

  15. Alkuraya FS. The application of next-generation sequencing in the autozygosity mapping of human recessive diseases. Human genetics. 2013;132:1197-211.
  16. Indexed at, Google Scholar, Cross Ref

  17. Petersen MB, Willems PJ. Non?syndromic, autosomal?recessive deafness. Clinical genetics. 2006 May;69(5):371-92.
  18. Indexed at, Google Scholar, Cross Ref

  19. Eikenboom JC. Recessive inheritance of von Willebrand's disease type I. The Lancet. 1993 Apr 17;341(8851):982-6.
  20. Indexed at, Google Scholar, Cross Ref

Get the App