Commentary - Journal of Parasitic Diseases: Diagnosis and Therapy (2023) Volume 8, Issue 2

Sub-atomic diagnostics and the study of disease transmission of a complete survey of finding.

Ruanpanun Zhang^*

Department of Biology, Federal Rural University of Pernambuco, Rua Dom Manoel de Medeiros, Dois Irmaos, Recife, Brazil

*Corresponding Author:

Ruanpanun Zhang
Department of Biology
Federal Rural University of Pernambuco
Rua Dom Manoel de Medeiros
Dois Irmaos, Recife, Brazil
E-mail: zhangpanum@db.ufrpe.br

Received: 14-Mar-2023, Manuscript No. aapddt-23-91355; Editor assigned: 15-Mar-2023, PreQC No. aapddt-23-91355 (PQ); Reviewed: 25-Mar-2023, QC No. aapddt-23-91355; Revised: 23-Apr-2023, Manuscript No. aapddt-23-91355 (R); Published: 29-Apr-2023, DOI: 10.35841/2591-7846-8.2.144

Citation: Zhang R. Sub-atomic diagnostics and the study of disease transmission of a complete survey of finding. J Parasit Dis Diagn Ther 2023;8(2):144

Introduction

Parasitic diseases continue to pose significant health challenges worldwide, affecting millions of people annually. Traditional diagnostic methods for parasitic infections, such as microscopic examination and serological tests, have limitations in terms of sensitivity, specificity, and turnaround time. However, the advent of molecular diagnostics has revolutionized the field by providing rapid and accurate identification of parasites.

Molecular diagnostics involve the detection and characterization of pathogens at the molecular level, primarily through nucleic acid-based techniques. Polymerase Chain Reaction (PCR) is one of the most widely used molecular methods in parasitology. It allows for the amplification and detection of specific DNA sequences from parasites, even in low concentrations. Additionally, DNA sequencing techniques provide valuable information about parasite species and strains, aiding in the identification of drug-resistant strains and guiding targeted therapy [1-3].

Applications of molecular diagnostics in parasitic diseases are vast. It enables the early detection of parasites, even during the pre-patent period when traditional methods fail to detect the infection. Molecular tests have shown high sensitivity and specificity in diagnosing various parasitic infections, including malaria, leishmaniasis, trypanosomiasis, and filariasis. These tests have also facilitated the identification of mixed infections and differentiation between closely related species, which is crucial for appropriate treatment strategies [4,5].

Molecular diagnostics has not only improved diagnostic accuracy but has also guided targeted therapy for parasitic diseases. By identifying drug-resistant strains, it helps in selecting the most effective treatment regimens. Furthermore, molecular tools can monitor treatment efficacy by detecting the presence or absence of parasites post-treatment, aiding in assessing cure rates and preventing the development of drug resistance.

Despite its significant advantages, there are challenges associated with implementing molecular diagnostics in resource-limited settings. The technique requires specialized laboratory equipment, skilled personnel, and quality control measures. However, efforts are underway to develop simplified and affordable molecular diagnostic platforms that can be utilized in low-resource settings, thereby expanding access to accurate diagnosis and appropriate treatment.

Conclusion

In conclusion, molecular diagnostics has revolutionized the field of parasitic disease diagnosis and therapy. It offers rapid and accurate identification of parasites, enabling early detection and targeted treatment. With ongoing advancements and efforts to improve accessibility, molecular diagnostics has the potential to transform the landscape of parasitic disease management. It holds promise in reducing morbidity and mortality associated with parasitic infections, especially in areas where these diseases are endemic.

References

1. Huggins LG, Koehler AV, Gasser RB, et al. Advanced approaches for the diagnosis and chemoprevention of canine vector-borne pathogens and parasites—Implications for the Asia-Pacific region and beyond. Adv Parasitol. 2023;120:1-85.

Indexed at, Google Scholar, Cross Ref

2. Amaral FU, Zorzi NR, Soveral LF, et al. Molecular diagnosis of abdominal angiostrongyliasis by PCR using serum samples. Parasitology Research. 2023;122(2):381-5.

Indexed at, Google Scholar, Cross Ref

3. Sow D, Sylla K, Dieng NM, et al. Molecular diagnosis of urogenital schistosomiasis in pre-school children, school-aged children and women of reproductive age at community level in central Senegal. Parasites & Vectors. 2023;16(1):1-0.

Indexed at, Google Scholar, Cross Ref

4. Knapp J, Lallemand S, Monnien F, et al. Real-time multiplex PCR for human echinococcosis and differential diagnosis. Parasite. 2023;30.

Indexed at, Google Scholar, Cross Ref

5. Flaspohler J, Forness M, Bye M, et al. Molecular surveillance detects the zoonotic nematode parasite Toxocara in soils from public spaces in a Minnesota community. Bios. 2023;93(4):124-31.

Google Scholar